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1、纟颉沙坦联合卡托普利治疗76例慢性心力衰竭的疗效观察doi：10.3969/j.issn.1007-614x.2014.2.6摘要目的：探讨纟颉沙坦联合卡托普利治疗慢性心力衰竭的临床效果。方法：2012年1月-2013年8月收治慢性心力衰竭患者152例，随机分成对照组和观察组，各76例，对照组给予纟颉沙坦80mg/次？H,连续治疗8周。观察组在对照组的基础上加用卡托普利进行治疗。结果：观察组治疗前LVESV(185.6±27.9)ml,治疗后(162.1±23.8)ml；LVEDV治疗前(128.5±25.8)ml,治疗后(99.8±24.9)ml；LVEF
2、治疗前(31.1%土&9%),治疗后(40.1%±10.l%)o对照组治疗前LVESV(183.6±29.3)ml,治疗后(32.6±8.8)ml；LVEDV治疗前(127.2+29.9)ml,治疗后(101.8±27.9)ml；LVEF治疗前(31.1%土&9%),治疗后(3&1%±11・1%)。两组治疗前后LVESV、LVEF、LVEDV比较差异无统计学意义(P>0.05),两组治疗后观察组明显优于对照组，两组比较差异有统计学意义(P〈0.05),观察组总有效率为89.5%,对照组总有效率为64.5%,两组比较差异有统计学意义(P〈0・05)。结论：纟颉
3、沙坦联合卡托普利治疗慢性心力衰竭的疗效显著。关键词慢性心力衰竭绷沙坦卡托普利Theefficacyofvalsartanandcaptopriltreat76patientswhohaschronicheartfailureHeZhiqiDepartmentofCardiologyofHenanYimaCoalIndustryGroupGeneralHospital,472300AbstractObjective：Toinvest!gatetheclinicaltreatmentofvalsartanandcaptoprileffectsofchronich
4、eartfailure.Methods：chronicheartfailuregroupandobservationgroup,the76patientsincontrolgroupweregivenvalsartanJanuary2012-August2013152patientswithtreated,wererandomlydividedintocontrolgroupwithcaptopri180mg/times?dayfor8weeks.Toobservethetreatmentonthebasisofthecontrolgroup.ResuIts
5、：BeforetreatmentLVESV185.6+27.9ml,aftertreatment162.1+23.8ml,LVEDVbeforetreatment128.5±25.8ml,aftertreatment99.8±24.9ml,LVEFbeforetreatment31<1%±8.9%,aftertreatment40.l%±10.1%inthecontrolgroupbeforetreatmentLVESV183.6土29.3ml,aftertreatment,32.6±8.8ml,LVEDVbeforetreatment127.2±29.9m
6、l,aftertreatment101.8±27.9ml,former31.1%土&9%LVEFaftertreatment3&1%±11.1%,beforeandaftertreatmentLVESV,LVEF,LVEDVwasnosignificantdifference(P>0.05),aftertreatment,theobservationgroupthanthecontrolgroup,thetwogroupshadsignificantdifference(P<0.05)observationgroup,thetotaleffectiverat
7、ewas89.5%inthecontrolgroup,thetotaleffectiveratewas64.5%,therewasasignificantdifference(P<0.05)groups.Conelusion：Theeffectofvalsartanandcaptopriltreatmentofchronicheartfailureisworthpromoting.KeywordsChronicheartfailure；Valsartan；Captopril慢性心力衰竭是心血管科常见的一种疾病，近年来，由于人们饮食习惯和生活习惯的改变，高血压
8、、高血脂的发病率逐步升高，慢性心力衰竭的发病率也逐步
