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《补肾固精法联合低分子肝素治疗小儿肾病综合征疗效分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、辽宁中医杂志2014年第41卷第4期·747·DOI:10.13192/j.issn.1000-1719.2014.04.062补肾固精法联合低分子肝素治疗小儿肾病综合征疗效分析郝世军,谢卓敏(1.温岭市第一人民医院肾内科,浙江温岭317500;2.温岭市第一人民医院手术室,浙江温岭317500)摘要:目的:探讨补肾固精法联合低分子肝肾对小儿肾病综合征的I当床疗效。方法:48例患儿随机分为两组,对照组采用强的松片治疗,观察组在此基础上采用固精丹联合低分子肝素治疗,比较两组疗效、中医证候积分和生化指标变化。结果:观察组有效率87.50%,对照组有效率66.67%,两组有效率比较差异有统计意义(
2、Ridit=19.356,P=0.000);治疗后,观察组尿蛋白排泄率(UAER)、血肌酐(Scr)、尿素氮(BUN)、24h尿蛋白定量及总胆固醇(TC)与对照组相比均具有统计学意义(P<0.05);中医证候积分下降高于对照组,差异有统计学意义(P<0.05)。结论:补肾固精法与低分子肝素联合,可以改善肾病综合征患儿临床症状,改善机体代谢水平,减轻中医证候积分,对肾脏具有明显保护作用。关键词:补肾固精法;低分子肝素;肾病综合征中图分类号:R692文献标志码:B文章编号:1000—1719(2014)04-0747-03TherapyEficacyAnalysisofInvigoratingK
3、idneyandFixingSpermMethodwithLowMolecularHeparinforChildrenwithNephroticSyndromeHA0Shijun,XIEZhuomin(1.NephrologyDepartment,TheFirstPeoplegHospitalofWenling,Wenling317500,Zhejiang,China;2.OperatingRoom,TheFirstPeople~HospitalofWenling,Wenling317500,Zhejiang,China)Abstract:Dctive:Tostudytheclinicalc
4、urativeeffectofkidneyandfixingspermmethodcombinedlowmolecularhepafinforchildrenwithnephroticsyndrome.Methods:48easeswererandomlydividedinto2groups.ThecontrolgroupwastreatedbyprednisonepieceandtheobservationgroupusedGujingdanwithlowmolecularheparintherapy,comparingthecurativeeffect,TCMsyndromeintegr
5、alandbiochemicalindicatorsoftwogroups.Results:Theobservationgroupseffectivenesswas87.50%andthecontrolgroupswas66.67%andtherewasstatisticalsignificancebetweentwogroups(Ridit=19.356,P=0.000).Aftertreatment,urinaryalbuminexcretionrate(UAER),scramcreatinine(Scr),ureanitrogen(BUN),24hurineproteinquantit
6、ativeandtotalcholesterol(TC)oftheobservationgroupwerestatisticallysignificantcomparedwiththoseofthecontrolgroup(P<0.05).TCMsyndromeintegraldropwashigherthanthatofthecontrolgroupandthedifferencewasstatisticallysignificant(P<0.05).Conclusion:Theinvigoratingkidneyandfixingspermmethodwithlowmolecularhe
7、pafincanimproveclinicalsymptomsofchildrenwithnephroticsyndrome,improvethebodysmetabolismandreducetheTCMsyndromeintegra1.Ithasobviousprotectiveeffectonkidney.Keywords:invigoratingkidneyandfixingspermmethod;l
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