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时间:2020-11-24
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1、BronchogenicCarcinoma(LungCancer)RespiratorydepartmentDefinitionBronchogeniccarcinomareferstothemalignanttumorwhichgrowsinthebronchus.Originatingfrommucusorglandofbronchus.IncidenceandmortalityBronchogeniccarcinomahasincreasedremarkableinincidenceandmortalityduringhalfofthecentury
2、andhasbecomethemostfrequentvisceralmalignantdiseasesofmen.Themortalityoflungcancerholdthefirstplaceamongallkindscarcinomas.EtiologyThecauseoflungcancerisunknown.Itisbelievedthattherearefollowingrelatedfactors.1.Excessivecigarettesmoking:Smokingindex(BrinkmanIndex)isequaltocigarette
3、sperdaysmokingtime(years).Passivesmokingisalsoacarcinogenfactor.Etiology2.Atmosphericpollution.Itwasfoundthatcarcinogenicfactorisbenzpyrene.3.Occupationalfactors.4Radioactivityintheatmosphere.5.DietsandNutrition.6.Chronicirritation.7.Geneticfactors.PathologyAndClassification1.Acco
4、rdingtothepositionoftumorarisingfrom,itcanbedividedintotwotypes.Centraltype:Tumorarisesfrommainbronchus,lobarandsegmentalbronchus.Peripheraltype:Tumorarisesbeyondsegmentalbronchus.PathologyAndClassification2.Accordingtocytology,itisconvenienttoclassifyintofourkindsoftypes.(1).Squam
5、ouscellcarcinoma.(2).Smallcellanaplasticcarcinoma.(3).Largecellanaplasticcarcinoma.(4).Adenocarcinoma(includingalveolarcellcarcinoma).PathologyAndClassificationAccordingtothedifferentprinciplesofmanagement,itisdividedintotwotypes.SCLC:smallcelllungcarcinoma.NSCLC:nonsmallcelllungca
6、rcinoma.ClinicalfeaturesTherearenosymptomsofearlylungcancerinsomepatients.Symptomscausedbylungcancerarenon-specific:perhapsanaudiblewheezeoraslightcough,symptomsofinfection(fever,purulentsputum),ofobstruction(wheezing,dyspnea),orulcerationofbronchialmucosa(hemoptysis).Clinicalfeatu
7、res1.Respiratorysymptoms.(1).Cough:(2).Hemoptysis:(3).Dyspnea.:(4).Wheezeorstridor:(5).Chestpain:(6).Fever:Clinicalfeatures2.Symptomscausedbythenearorgansortissueinvolvedbytumor.(1).Dysphagia.(2).Hoarseness.(3).Pleuraleffusionduetoinvasionofthepleura.ClinicalFeatures(4).Horner’ssyn
8、drome.Itiscausedbyinvading
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