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ID:70132234
大小:9.12 MB
页数:69页
时间:2021-11-16
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1、5.HomeoticselectorgeneMasterregulatorygenefunctionalcharacters:Constitution:Homeoticgenecomplex,HOM-C:Antennapediacomplex,Antp-CBithroaxcomplex,BX-CLocationinthechromosomeandtheirexpressionpatterns:Dosophila:Location:Expressioncharacter:Mammals:mouseandmanLo
2、cation:hoxA1-13:mouse(6)/man(7)hoxB1-13:mouse(11)/man(17)hoxC1-13:mouse(15)/man(12)hoxD1-13:mouse(2)/man(2)Expressioncharacter:1)~5)1)Antennapediacomplex,Antp-CComponentsofantp-C:labdfd:pb:scr:antp:GenestructureofAntpC2)Bx-CComponentsofBx-C:ubxabd-Aabd-Bcaud
3、alGenestructureofBx-C:ubx:abx(ppx,bx)(75kb)bxd(pbx,bxd)(25kb)notranslationBx-C:3’ubx(100kb)(covering1/3ofBx-C)–abdA-abdB-(covering2/3ofBx-C)二、thedevelopmentoflimbbud1.Originoflimbbudlimbbud:limb-budmesodermlimb-budectodermApicalectodermridge(AER):epitrichial
4、layerbasallayer2.ProspectivelimbarearingoftissueLimbfield(harmoniousequipotentialsystem)3.embryonicfieldharmoniousequipotentialsystem4.limbaxesproximal-distal,P-Daxisdorsal-ventral,D-Vaxisanterior-posterior,A-Paxis1)proximal-distal,P-Daxis2)dorsal-ventral,D-
5、Vaxis3)anterior-posterior,A-Paxis
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