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1、女性生殖道解脲支原体及人型支原体感染680例的耐药性分析【摘要】目的了解本地区女性生殖道解脲支原体（Uu）及人型支原体（Mh）感染率及对不同药物的耐药情况。方法采用女性子宫颈管分泌物培养+药敏法进行支原体感染及耐药性分析。结果在680例女性患者中，Uu、Mh、Uu+Mh阳性率分别为60.59%，12.35%，6.91%；药敏试验结果显示：Uu对喹诺酮类药物环丙沙星、可乐必妥、司帕沙星的耐药率居10种抗菌药前列，耐药率分别为92.71%、32.52%、26.94%；Uu对交沙霉素、强力霉素、克拉霉素敏感，敏感率分别为95.36%、91.99%、87
2、.86%；Mh则对环丙沙星、红霉素、罗红霉素的耐药率高，耐药率分别为91.67%、80.95%、80.95%；Mh对强力霉素、交沙霉素、克拉霉素较为敏感，敏感率分别为73.81%、70.24%和47.62%。结论Uu对环丙沙星、可乐必妥、司帕沙星的耐药率高，Mh则对环丙沙星、红霉素、罗红霉素耐药率高，Uu和Mh均对交沙霉素和强力霉素敏感，可作为治疗支原体感染的首选抗生素和经验用药。【关键词】支原体；药物耐药性；生殖道Analysison680casesoffemaleinfectionanddrugsensitivitytestofureapla
3、smaurealyticumandmycoplasmahominis8［Abstract］ObjectiveTofindouttheinfectionpercentageoflocalfeminineureaplasmaurealyticum（Uu）andmycoplasmahominis（Mh）andtheantibioticsresistanceofdifferentdrugs.MethodsWeusedthefeminineendocervicalsecretionsraiseandmedicinesensitivemethodtocarr
4、yontheanalysisofthemycoplasmainfectionandtheantibioticsresistance.ResultsAmongthe680femininepatients,positiverateofUuwas60.59%,ofMhwas12.35%,ofUuandMhwas6.91%;TheresultofMedicinesensitiveexperimentationwasthattheUu’santibioticsresistanceofquinolonecompoundssuchasciprofloxacin
5、,cravittabletsandsparfloxacinwasthefirstoftenkindsofantibacterialmedicines,antibioticsresistancerateofciprofloxacinwas92.71%,ofcravittabletsin32.52%,ofsparfloxacinwas26.94%,Uuwassensitivetojosamycin,doxycyclineandclarithromycin,sensitiverateofjosamycinwas95.36%,ofdoxycyclinew
6、as91.99%,ofclarithromycinwas87.86%,Mh’santibioticsresistanceofciprofloxacin,erythromycinandroxithromycinwashigh,antibioticsresistancerateofciprofloxacinwas91.67%,oferythromycinwas80.95%,ofroxithromycinwas80.95%,Mhwassensitivetodoxycycline,josamycinandclarithromycin,sensitiver
7、ateofdoxycyclinewas73.81%,of8josamycinwas70.24%,ofclarithromycinwas47.62%.ConclusionUu’santibioticsresistanceofciprofloxacin,cravittabletsandsparfloxacinishigh,Mh’santibioticsresistanceofciprofloxacin,erythromycinandroxithromycinishigh,UuandMharesensitivetojosamycinanddoxycyc
8、line,amongalltheantiauxinsandclassicmedications,theyarethefirstchoic
