lrrk2基因多态与中国汉族散发性帕金森病的相关性研究

《lrrk2基因多态与中国汉族散发性帕金森病的相关性研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号：R743.32学校代码：10392学科专业代码：100204学号：2101003547福建医科大学硕士研究生毕业论文LRRK2基因多态与中国汉族散发性帕金森病的相关性研究ResearchontheassociationbetweenLRRK2genepolymorphismandsporadicParkinson’sdiseaseinaChineseHanpopulation学位类型：医学硕士所在学院：第一临床医学院研究生：卢红腾学科、专业：神经病学导师：马琪林副教授研究起止日期：2011年7月至2013年2月答辩日期：2013年5月24日二○一三年五月目录摘要···········

2、······························································1缩略词表······································································5第一章引言·······························································6第二章材料与方法·························································81研究对象·····················

3、·······························································82诊断与排除标准··········································································83实验材料··················································································104实验方法··························································

4、························125统计分析··················································································16第三章结果······························································181临床基本资料比较·····································································182LRRK2基因外显子34和11PCR扩增产物鉴定··········

5、························193LRRK2基因外显子34和11多态位点测序图·····································204序列分析··················································································245Hardy-Weinberg平衡法则吻合度检验············································246LRRK2基因S1647T及K1637K的基因型频率和等位基因频率················25

6、第四章讨论······························································30第五章结论······························································34参考文献·····································································35综述·········································································41读硕士期间发表的论

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