慢性乙型肝炎脾虚证候量表研制初探

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1、·6·上海中医药杂志2008年第42卷第3期SH.J.TCMMar.,2008;Vo1.42No.3杏苑之星慢性乙型肝炎脾虚证候量表研制初探乐敏黄杏高月求上海中医药大学附属曙光医院（上海200021）【摘要】目的探索建立慢性乙型肝炎脾虚证候量表的方法。方法通过收集文献中有关慢性乙型肝炎脾虚证的主要证候，结合专家问卷调查结果，形成初始量表；对50例慢性乙型肝炎脾虚证患者进行小样本预调查，以t检验、方差分析、因子分析和相关性检验的方法对调查结果进行条目分析，并对初始量表的条目予以修正，形成慢性乙型肝炎脾虚证候量表；利用量表测试

2、241例慢性乙型肝炎脾虚证患者，从效度、信度、反应度等3个方面评价量表的价值。结果编制出含10个条目的慢性乙型肝炎脾虚证候量表，分为腹胀、纳差、乏力、神疲嗜睡、便溏、衄血6个维度；该量表的周重测信度为0.928，Cronbach’sα系数为0.744，因子分析提取出两个公因子，累计方差贡献率为79.24%；各维度与总分的相关系数均在0.73以上。结论该量表可较好地区分病情程度，较为灵敏地反映中医疗效。【关键词】慢性乙型肝炎；脾虚证；量表；信度；效度【中图分类号】R512.6+2；R256.4【文献标识码】A【文章编号】10

3、07-133（42008）03-0006-04EstablishmentofMeasurementScaleforSpleenDeficiencySyndromeinChronicHepatitisBLEMinHUANGXingGAOYue-qiuShuguangHospitalAffiliatedtoShanghaiUniversityofTraditionalChineseMedicineAbstract:ObjectiveTodevelopaspecificscaleforthechronichepatitisBpa

4、tientswithspleendeficiencysyndrome.MethodsBycollectinginformationonspleendeficiencysyndromeofchronichepatitisBbasedonrelatedmedicalliteratureandenquiringquestionnaire,werevisethedraftscalebyperformingasmall-scalesurveyon50chronichepatitisBpatientswithspleendeficie

5、ncy.Performateston241chronichepatitisBpatientswithspleendeficiencyandevaluatethescalefromtheperspectivesofvalidity,reliabilityandresponsiveness.AllthefiguresareprocessedwithstatisticsoftwareSPSS11.5.Detailedmethodisasfollows:evaluatereliabilitybyusingPearsonCorrel

6、ationandpairedt-test,evaluateconsistencybetweenitemsbyusingCronbach’salphamodulus,validitybyusinggeneanalysis,andinvestigatewhethersignificantdifferenceexistsbetweentwoindependentsamplesbyusingindependentsamplebasedt-test.ResultsScaleforspleendeficiencysymptomsofc

7、hronichepatitisBcontains10items,representing6dimensions,whichareabdominaldistention,badappetite,tiredness,sleepiness,loosestools,andbleedingfromnoseandteeth.Thetest-retestcorrelationcoefficientofthescaleis0.928,whichmeanssignificantreliabilityexistsbetweenresultso

8、ftwotests.Cronbach’sαofthescaleis0.744,whichmeansitemsareconsistentwitheachother.Twopublicfactorsareextractedfromfactoranalysiswhilecumulativevarianceis