病理学绪论病理学图片Introdu

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1、PathologySecondEditionEditorinchief:CHENJieandLIGandiPeople’sMedicalPublishingHouseTextbookIntroductiontopathologyPekingUnionMedicalCollegeChenJieIntroductiontopathologyAbridgingdisciplineinvolvingbothbasicscienceandclinicalpractice.Devotedtothestudyofthestructuralandfunctionalchangesincells,tissues

2、andorgansthatunderliedisease.Toexplainthewhysandwhereforesofthesignsandsymptomsofthepatients.Providingasoundfoundationforrationalclinicalcareandtherapy.PathologyThestudyofetiologyofthediseaseThestudyofpathogenesisofdiseaseThestudyofmorphologicalchangesofdiseaseThemostimportantdiagnosisinmodernmedica

3、lpracticeTheimportantstepinevidence-basedmedicineThefunctionalconsequencesofthemorphologicchanges(clinicalsignificance)PathologyBiopsyHistopathologyCytologyElectromicroscopyResectedspecimensHistochemistryAutopsyMicrobiologyCell&tissuecultureimmunohistochemistryMolecularpathologyEtiologyIntrinsicorge

4、neticAcquiredinfectiousnutritionalchemicalphysicalPathogenesisInitialstimulus-------->ultimateexpressionofdiseaseDefectivegene-------->cystsandfibrosisMorphologicchangesStructuralalterationscellstissuesorgansCharacteristicofthediseaseDiagnosticoftheetiologicprocessClinicalsignificanceFunctionalabnor

5、malityClinicalfeatures(symptomsandsigns)ClinicalcoursePrognosisofthedisease“Asisourpathology,soisourmedicine”“病理为医之本”SirWilliamOsler1849-1919基础医学课目中与临床最接近的当推病理学，因为它是临床与基础之间的桥梁，要学好临床先要学好病理学，我毕业后才认识这个道理。原想加学一年病理学以资祢补，可是没能做到，至今引为遗憾。——著名医学家张孝骞谢谢