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时间:2020-05-14
《抗核抗体、自身免疫性抗体与慢性乙肝的关系及护理对策分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、《中国医学创新》第12卷第12期(总第330期)2015年4月医学综合Yixuezonghe抗核抗体、自身免疫性抗体与慢性乙肝的关系及护理对策分析米刘育琼①魏桂菊①何秋娴①【摘要】目的:研究抗核抗体(ANA)、自身免疫性肝病抗体(LSA)与慢性乙型肝炎的关系及护理对策。方法:选择2013年3月一2014年3月在本院接受治疗的慢性乙肝患者100例作为研究对象(慢性乙肝组),另选92例在本院接受健康体检的正常人员作为对照组。对比两组相关抗体情况,CHB自抗阳性、阴性组相关指标情况,护理前后患者的治疗依从性情况。结果:慢性乙肝组的ANA阳性率为24.00%(24/100),显著高于对照组的4.35
2、%(4/92),差异有统计学意义(P<0.05oCHB自抗阳性组的层黏连蛋白(LN)和透明质酸酶(HA),以及Ⅳ型胶原水平均显著高于自抗阴性组,差异均有统计学意义(P0.05o护理后慢性乙肝患者的治疗依从性显著高于护理前,差异有统计学意义(P<0.05o结论:慢性乙肝患者血清中存在较多抗体,但ANA及肝病相关抗体测定对于预测患者预后和转归具有较大的意义,其可能是导致乙肝后肝硬化的一种病因。同时,为患者制定护理对策并施以护理能增加治疗依从眭,值得临床重视。【关键词】抗核抗体;自身免疫性肝病抗体;慢性乙型
3、肝炎;关系;护理对策RelationshipandNursingCountermeasuresofAnfinuclearAntibodies.LiverSpecificAutoantibodieswithChronicHepatitisB/LIUYu—qiong.WEIGui-ju,HEQiu-xianJ/MedicalInnovationofChina,2015,12(12):097—1O0【Abstract】0bjective:Tostudyrelationshipandnursingcountermeasuresofantinuclearantibodies。liverspecific
4、autoantibodieswithchronichepatitisB.Method:FromMarch2013toMarch2014inourhospitalfortreatmentof100casesofpatientswithchronichepatitisB(CHB)astheresearchobject.Chose92casesinourhospitalreceivedphysicalexaminationofnormalpersonsascontrolgroup,therelatedantibodies,CHBfrompositiveandnegativegroupofrelat
5、edindicators,nursingcareofpatientsbeforeandaftertreatmentadherenceoftwogroupswerecompared.Result:ChronichepatitisBgroup’sANApositiveratewas24.00%(241100),wassignificantlyhigherthanthecontrolgroup’s4.35%(4/92),thediferencewasstatisticallysignificant(P6、esionproteins(LN)andhyaluronicacid(HA),andcollagentypeⅣlevelsweresignificantlyhigherthanthenegativeresistancegroups,differenceswerestatisticallysignificant(P<0.05).TwogroupsinALT,AST,HBVquantitativewascontrastandHBVparting,therewerenostatisticallysignificantdifference(P>O.05).Afternumingoftreatment7、adherenceforpatientswithchronichepatitisBwassignificantlyhigherthanbeforetreatment,thedifferencewasstatisticallysignificant(P<0.05Conclusion:Therearemoreantibodyinse/qlmofpatientswithchronichepatitisb,butth
6、esionproteins(LN)andhyaluronicacid(HA),andcollagentypeⅣlevelsweresignificantlyhigherthanthenegativeresistancegroups,differenceswerestatisticallysignificant(P<0.05).TwogroupsinALT,AST,HBVquantitativewascontrastandHBVparting,therewerenostatisticallysignificantdifference(P>O.05).Afternumingoftreatment
7、adherenceforpatientswithchronichepatitisBwassignificantlyhigherthanbeforetreatment,thedifferencewasstatisticallysignificant(P<0.05Conclusion:Therearemoreantibodyinse/qlmofpatientswithchronichepatitisb,butth
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