芍甘颗粒提取、精制工艺线路设计

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1、中药制药分离工程课程设计目录1.设计任书···················································032.设计概述···················································042.1处方··················································042.2用法··················································042.3功能主治·····························

2、··················042.4药理作用···············································042.5颗粒剂介绍·············································053.常用精制技术简介············································063.1常用精制分离方法······································0621中药制药分离工程课程设计3.2简析·························

3、··························064.课程实验····················································085.工艺路线设计················································155.1处方···················································155.2制备工艺···············································155.3工艺流程及工艺说明··········

4、···························165.3.1工艺流程···········································165.3.2工艺说明···········································175.4提取物生产过程数据表····································186.结束语21中药制药分离工程课程设计·····················································197.参考文献··············

5、·····································19设计任务书一、设计题目芍甘汤提取、精制工艺设计水提醇沉二、设计条件（1）芍甘复方颗粒剂提取物二、设计内容与要求（1）确定提取工艺及参数；（2）确定精制分离工艺及参数；（3）提取物得率、成分含量以及相对密度；（5）编写设计说明书；三、设计成果（1）设计说明书一份包括概述（简要说明所设计的复方中药效物质成分类型、性质及药理作用等）；常用精制分离技术简述（主要为高速离心、醇沉、大孔树脂吸附以及超滤）课程实验（不同精制方法的效果及比较）；工艺线路的设计（从最终制剂的剂型、工艺合理性以及生产

6、成本等方面考虑）。（2）芍甘汤提取精制工艺流程图；21中药制药分离工程课程设计四、设计时间设计时间为2周，从2013年5月12日至2013年5月26日。一、概述1、处方组成甘草12g芍药12g芍药【来源】本品为毛茛科植物芍药PaeonialactifloraPall.的干燥根。夏、秋二季采挖，洗净，除去头尾和细根，置沸水中煮后除去外皮或去皮后再煮，晒干。【药性】苦、酸，微寒。归肝、脾经。【功效】养血调经，敛阴止汗，柔肝止痛，平抑肝阳。【主治】用于血虚萎黄，月经不调，自汗，盗汗，胁痛，腹痛，四肢挛痛，头痛眩晕。甘草【来源】本品为豆科植物甘草Glycyrrhiz

7、auralensisFisch.、胀果甘草GlycyrrhizainflataBat.或光果甘草GlycyrrhizaglabraL.的干燥根和根茎。春、秋二季采挖，除去须根，晒干。【药性】甘，平。归心、肺、脾、胃经。【功效】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。【主治】用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。2、用法21中药制药分离工程课程设计取上述2味，加600mL水煎煮至300mL，取液去渣，温服。3、功能主治本方主治津液受损，阴血不足，筋脉失濡所致诸证。由芍药和甘草组成；方中芍药酸寒，

8、养血敛阴，柔肝止痛；甘草甘温，健脾益气，缓急止痛。二