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1、14C呼气试验与快速尿素酶试验检测幽门螺杆菌感染的对比研宄［摘要］目的：探讨14C呼气试验和快速尿素酶试验两种方法对幽门螺杆菌(H.pylori)感染的诊断价值。方法：107例有消化道症状的患者，分别用14C呼气试验和快速尿素酶试验两种方法进行检测，比较两种方法对H.pylori检测符合率及灵敏度、特异度、阳性预测值和阴性预测值。结果：两种方法对H.pylori感染的检出率分别为92.0%和89.8%，但差异无统计学意义。14C呼气试验的灵敏度、特异度、阳性预测值和阴性预测值分别为92.7%、88.0%、93.8%和84.6%。快速尿素酶试验灵敏度、特异度、阳性预测值和阴性预测值分别为87.8
2、%、80.0%、91.1%和71.4%。结论:14C呼气试验和快速尿素酶试验对H.pylori感染的诊断均有很高的敏感性和特异性，是临床上用于H.pylori感染诊断的可靠方法。［关键词］14C呼气试验；快速尿素酶试验；幽门螺杆菌；感染［中图分类号］R446.1［文献标识码］C［文章编号］1674-4721(2011)11(c)-074-02Comparationofthedifferenceofdiagnosticvaluebetween14C-ureabreathtestandrapidureasetestforhelicobacterpyloriInfectionLIHui,TANLir
3、angl,YlMingl,HEBincen2,FENGYutao31.DepartmentofGastroenterology,theCentralHospitalofBazhongCity,SichuanProvince,Bazhong636000,China;2.Departmentofgynaecology,theCentralHospitalofBazhongCity,SichuanProvince,Bazhong636000,China;3.Departmentofstomatology,theCentralHospitalofBazhongCity,SichuanProvince,
4、Bazhong636000,China[Abstract]Objective:Tocomparethedifferenceofdiagnosisvaluebetween14C-ureabreathtestandrapidureasetestindetectinghelicobacterpylori.Methods:Asampleof107outpatientswithdigestivetractsymptomwerescreenedforhelicobacterpyloriinfectionwith14C-ureabreathtest(UBT),rapidureasetest(RUT)onfr
5、eshbiopsy.Directsmearmethodwasusedasgoldstandard.Sensitivity,specificity,positiveandnegativepredictivevalueswerecalculatedandcompared.Results:ThedetectableratesofH.pyloriwere92.0%and89.8%testedbytwomethods,therewereusuallynosignificantdifference.Sensitivities,specificities,positivepredictivevalueand
6、negativepredictivevaluewere92.7%,88.0%,93.8%and84.6%respectively,forthe14C-ureabreathtest;Sensitivities,specificities,positivepredictivevalueandnegativepredictivevaluewere87.8%,80.0%,91.1%and71.4%,respectively,forrapidureasetest.Conclusion:Both14C-ureabreathtestandrapidureasetestshowahighaccuracytod
7、etectthehelicobacterpyloriinfection.Theyaredependablemethodsforclinicalindetectinghelicobacterpylori.[Keywords]14C-ureabreathtest;Rapidureasetest;Helicobacterpylori;Infection幽门螺杆菌(helicobacterpylori，H
