]全自动血凝仪检测原理及临床应用

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1、］全自动血凝仪检测原理及临床应用PrincipleandclinicalapplicationofautomaticbloodcoagulationanalyzerWiththedevelopmentofmedicalscience,timelydiagnosisofbleedingandthromboticdiseases,clinicalobservation,analysisofanticoagulantdoseseemmoreandmoreurgent,andthetraditionalmanualmethodsandqualitativeexamin

2、ationofsinglesolidificationcannotsatisfytheclinicalrequirements,appearanceandapplicationoffullautomaticbloodcoagulationanalyzer,thethrombosisandhemostasisbecomesimpleandaccurateinspectionoftheprojectreliable,greattomeettheneedsofclinicaldiagnosisandtreatment・1basicmethodsofdetection

3、Atpresent,bloodcoagulationapparatusmostlyadoptsbiologicalmethods,andcanbedividedintothreekinds:currentmethod,viscositymethodandopticalmethod.OnepointoneCurrentmethod:thismethodisconductivewithplasmasamplesoffibrin,insertedelectrodeswerebroken,todeterminewhetherfibrinformationusingtw

4、ocurrentbetweentheelectrodes,anddeterminethesolidificationendpoint・OnepointtwoViscositymethod:alsocalledimmunomagneticbeadsanddetectionpartoftheinstrumentisindependentofthecoiltoproducethenecessaryfields,Leslingonthemeasuredmagneticbeadswereadded,thechangescausedbythemagneticfieldof

5、magneticbeadsinmotion,withplasmacoagulation,plasmaviscosityincreasedforsmallbeads,swinggraduallyreduced,theelectromagneticsensorintheinstrument,differentvolatilitydeterminationofsmallbeads,theplasmacoagulationtimecalculation.OnepointthreeOpticalmethod:thismethodisthemostfrequentlyus

6、edmethodofbloodcoagulationtest・Whentheplasmaisgraduallysolidifiedinthesamplecup,thefibrinogenchangesintofibrin,anditsphysiologicalpropertieschangeaswel1.Whenabeampassesthroughthesamplecup,theintensityofthetransmittedlightandastigmatismwillalsochange・1basicprinciplesofdetectionTurbid

7、imetryusesasubstanceintheplasmaasanantigen,andwhenantigenismixedwithanantibodyinthereagent,aspecificbindingreactionoccurstoproduceacompositeparticle,therebydeterminingthecontentofthesubstancetobedetected・Theprincipleis:thesameamountofantigenantibodybindinghascertainquantityrelations

8、hipbetweenthereacti