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1、ASTUDYOFTOOTHWHITENING:SAFETY,EFFICACYANDMECHANISMOFACTIONGerardKugel144144144144ASTUDYOFTOOTHWHITENING:SAFETY,EFFICACYANDMECHANISMOFACTION144144ASTUDYOFTOOTHWHITENING:SAFETY,EFFICACYANDMECHANISMOFACTIONDipartimentodiScienzeOdontostomatologicheUniversitàdiSienaVialeBracci531
2、00SienaPreparedforthegraduatecommitteeonJune13,2004GerardKugelBoston,MA,USA144144ThepresentthesisisrespectfullysubmittedtoProfPieroTosi,RectoroftheUniversityofSiena,toProfAlbertoAuteri,DeanoftheFacultyofMedicine,UniversityofSiena,toProfEgidioBertelli,vice-DeanoftheFacultyofM
3、edicineandDirectoroftheDepartmentofDentalScience,andtoProfMarcoFerrari,Pro-RectorforinternationalaffairsandPresidentofDentalSchool,UniversityofSiena.GraduateCommittee:PromotorProf.DrMarcoFerrariCommitteeProf.DrC.L.DavidsonProf.DrF.TayProf.DrToledanoProf.DrBalleriThisthesiswa
4、spreparedatTuftsUniversitySchoolofDentalMedicine,BostonMA,USAandattheSchoolofDentistryUniversityofSiena,Italy.144144ContentsChapters1Introduction2ANovelLowDoseTooth-WhiteningDeliverySystemEfficacyandSafety:ARandomizedandControlledClinicalTrialConcentrationandDoseResponseClin
5、icalTrialEvaluatingthePeroxideConcentrationResponseofaPolyethylenestripDeliverySystemover28Day4LightactivatedToothWhiteningClinicalEvaluationofa35%HydrogenPeroxideIn-OfficeWhiteningSystem5ChemicalVsLightactivatedToothWhiteningClinicalEvaluationofChemicalAndLight-ActivatedToo
6、thWhiteningSystemsToothwhiteninganditsEffectonEnamelandDentinDailyUseofWhiteningStripsonTetracyclineStainedTeeth:ComparativeResultsafterTwoMonths7LongTermHydrogenPeroxideExposureanditsEffectonDentinComparativeStudyof6.5%HydrogenPeroxideBleachingStripsonTetracyclineStain:Clin
7、icalResponseafterSixMonthsDailyUse8PaintondeliverysystemsAclinicalComparisonoftwoPaintonWhiteningSystems9MaintenanceofWhiteningClinicalStudytoEvaluatetheMaintenanceofWhiteningafterBleachingTreatment144144IntrapulpalTemperatureswithLightActivatedWhiteningEffectsofaLightActiva
8、tedBleachingSystemonPulpChamberTemperatureinVitroEffectofToothWhiteningonEn
