afp靶向uspio分子探针在肝癌特异性mr成像中的价值

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1、分类号：R445．2密级：单位代码：10422学号：200913352⑧∥菇办孚硕士学位论文论文题目：AFP靶向USP10分子探针在肝癌特异性MR成像中的价值SpecificMRimagingofhepatocellularcarcinomausingAFP—targetedUSPIOmolecularprobe合作导师2012年5月20[j原创性声明本人郑重声明：所呈交的学位论文，是本人在导师的指导下，独立进行研究所取得的成果。除文中已经注明引用的内容外，本论文不包含任何其他个人或集体己经发表或撰写过的科研成果。对本文的研究作出重要贡

2、献的个人和集体，均己在文中以明确方式标明。本声明的法律责任由本人承担。论文作者签名：垦丕垫日期：2翌垡．互：兰兰、关于学位论文使用授权的声明本人同意学校保留或向国家有关部门或机构送交论文的印刷件和电子版，允许论文被查阅和借阅；本人授权山东大学可以将本学位论文的全部或部分内容编入有关数据库进行检索，可以采用影印、缩印或其他复制手段保存论文和汇编本学位论文。(保密论文在解密后应遵守此规定)论文作者签名：堡查垫导师签1wl-．一日期：趣堡复：墨乡目录中文摘要···········································

3、·················l英文摘要·················································“”·······3符号说明···一“”····””一一一．．”···一．．······“一”一””．．““”6前言···························································．7刖舌。’’‘‘。‘。。‘‘。’。。。。。。。’。。。‘。。。‘。。。。。。。。。’。’。。。。。。‘‘。。‘‘。。。。。。一7参考文献··············

4、·············································．9第一部分AFP靶向USPIO分子探针在HepG2细胞分子成像中的价值研究材料与方法·····················································11结果···························································15讨{仑···························································16小

5、结··························································021附l蛩表························································．22参考文献·······················································25第二部分肝癌AFP靶向USPIO分子探针MR分子成像实验研究材料与方法··················································

6、··-27结果···························································30讨{仑···························································31／J、结···························································34附图表·························································35参考文献········

7、···············································39结论··························································"40综j鲞··························································"41致谢···························································49攻读学位期间发表的学术论文目录·················

8、····················50CoNTENTSChineseabstract····················································。1Engl