加味茵陈蒿汤保留灌肠对慢性重型肝炎患者内毒素和血氨的影响

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1、提要目的：观察加味茵陈蒿汤保留灌肠对慢性重型肝炎患者内毒素和血氨的影响，评价中药复方保留灌肠治疗慢性重型肝炎疗效。方法：临床选择纳入标准的湿热瘀毒型慢性重型肝炎60例，随机分为治疗组和对照组各30例，对照组在综合治疗的基础上给予乳果糖30mlpotid，治疗组在综合治疗的基础上给予加味茵陈蒿汤保留灌肠。比较两组的临床疗效。结果：研究结果显示，两组治疗后都能明显改善肝功能、降低并发症发生率。治疗组在改善临床症状及ALT、AST、TBIL、ALB、PTA方面优于对照组（P<0.01或P<0.05）；在降低内毒素和血氨的含量方面，其疗效明显优于对照组（P<0.01或P<0.05）。结论：

2、加味茵陈蒿汤保留灌肠能有效改善慢性重型肝炎的临床症状，改善肝功能，降低内毒素和血氨的含量，在临床应用中安全、有效。关键词加味茵陈蒿汤；保留灌肠；慢性重型肝炎；内毒素；血氨ModifiedYinchenhaoofChronicSevereHepatitisEffectsofEndotoxinandAmmonia,andToExploreItsMechanismSpecialty：InternalMedicineofTCMAuthor：QinShuxiaAuthor：ProfessorSunJianguangAbstractObjective:Toobservethetheflavor

3、edYinchenhaosoupretentionenemaofendotoxinandammoniainpatientswithchronicseverehepatitis,andtoexploreitsmechanism.Methods:Theclinicalselectthecriteriaforinclusionofdampheatandtoxicchronicseverehepatitis60caseswererandomlydividedintotreatmentgroupandcontrolgroup30cases,thecontrolgrouponthebasiso

4、fthecomprehensivetreatmentgivenlactulose30mlpotidtreatmentgroupinthecomprehensivetreatmentthebasisgiveflavoredYinchenhaoinsoupretentionenema.Clinicalefficacyofthetwogroupswerecompared.Results:Theresultsshowedthatthetwogroupsaftertreatmentcansignificantlyimproveliverfunction,reducetheincidenceo

5、fcomplications.Treatmentgroupthanthecontrolgroup(P<0.01orP<0.05)inimprovementofclinicalsymptomsandALTandAST,TBIL,ALB,PTA;inreducingthecontentofendotoxinandammonia,weresignificantlybetterthanthecontrolgroup(P<0.01orP<0.05).Conclusion:ModifiedYinchenhao,Decoctionenemacaneffectivelyimprovetheclin

6、icalsymptomsofchronicseverehepatitisandimproveliverfunction,reducethecontentofendotoxinandammonia,intheclinicalapplicationofsafeandeffective.Keywords:flavoredYinchenhaosoup;retentionenema;chronicseverehepatitis;endotoxin;ammonia目录引言..............................................................

7、......................................................................1研究内容与方法........................................................................................................................3一、病例选择...............................