高场mri在胎儿胼胝体发育过程与超声疑诊胼胝体发育不全胎儿中的应用价值

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1、山东人学坝lj学位论文ValueofhighfieldMRIondevelopmentofhumanfetalcorpuscallosumandfetalcorpuscallosumagenesisforUSsuspected．ABSTRACTObject1．Toestablishreferencerangesduringhumanpregnancyforno肌aIfetalcorpuscallosumdimensionsbyMRImeasurementsandstatistical觚alysis，facilitateamor

2、eobjectivediagnosisoffetalcorpuscallosumagenesis；2．ToexplorethevalueofMRIoncorpuscallosumagenesisforUSsuspected，comparisonwiththeimagingmanifestationandclinicalvalueofMRIandUS．Method1·Collectionof55normalfetusescasesdiagnosedbyMRIduring2005．2007，gestationalagefrom24

3、to36weeks，52fetusesabovefitformeasurementofMRI"rE。weightedMRimagingWasperformedusingHASTEandTi-weightedMRimagingwasusingFLASH．Onthebaseoffetalbrain’Sanatomicalstructurewasnormalviewingbymulti。planeimagineofMRI，thelengthoffetalcorpuscallosumandtheanteroposteriordiame

4、terofthebrainwasmeasuredatthemid．sagittalplane，thewidthWasmeasuredatthemid—coronalplane，thenstatisticsanalyzetheoutcomeofthemeasureandcalculatetheratioofthelengthofthecorpuscallosumtotheanteroposteriordiameterofthebrain．2．AfterprenatalscreeningbyUSusinghighresolutio

5、ntransabdominaltransducers，19casesarefetalcorpuscallosumagenesissuspected，theageofpregnantwomenisfrom20to37yearsold(average28years)andwithgestationfrom20to38weeks(average29weeks)werestudiedwitha1．5TsuperconductiveMRunitwithin24hours．T2一weightedMRimagingwasperformedu

6、singHASTEandTi。weightedMRimagingWasusingFLASH．ComparisonwiththediagnosisofMRIandUltrasoundweredonewithautopsyorfollow-upoutcomeandtheimagingmanifestationandclinicalvalueofMRIandUS．Results1·Thelengthandwidthoffetalcorpuscallosumshowagradualincreaseduringpregnancyfrom

7、24to36weeksandincreasedinalinearfashion．Thesizeofthe4山东人学坝Ij学位论文corpuscallosumasafunctionofgestationalagewasexpressedbyregressionequations：length(mm)=一4．349+1．395×gestationalage(weeks)；width(turn)=0．744+0．244Xgestationalage(weeks)．Thedimension—gestationalagecorrelat

8、ioncoefficientswere：r=0．875forlengthandr=0．604forwidth．thesewerestatisticallysignificant(P