糖痹宁联合甲钴胺治疗糖尿病周围神经病变的临床观察

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1、提要研究目的：观察糖痹宁联合西药治疗糖尿病周围神经病变的临床疗效以及相对于单纯西药治疗的优势。研究方法：采用前瞻性随机对照的方法，将符合诊断标准的60例糖尿病周围神经病变患者，随机分为治疗组与对照组，每组30例。在糖尿病基础降糖治疗(西医基础治疗）的基础上，治疗组予（口服）糖痹宁联合甲钴胺注射液500ug皮下注射，对照组予甲钴胺注射液500ug皮下注射，治疗观察8周，将治疗前后的临床症状评分及神经传导速度进行统计学分析。研究结果：两组患者治疗后在（中医症候评分）症状及神经传导速度两方面都得到明显改善，其中治疗

2、组总有效率83.33%，对照组总有效率63.33%。糖痹宁联合西药治疗在患者症状改善、神经传导速度方面明显优于对照组(P<0.05)。结论：糖痹宁联合甲钴胺在治疗气阴两虚兼血瘀型糖尿病周围神经病变有良好的疗效，且安全性良好，提供了中医药治疗周围神经病变的新思路。关键词：糖尿病周围神经病变；糖痹宁；甲钴胺注射液；中西医结合疗法TheclinicalResearchofTangbingningcombinedwithcobaltammoniuminjectiontreatingDiabeticPeripheral

3、NeuropathySpecialty:TraditionalChineseInternalMedicineAuthor:WangtingtingTutor:ProfessorZhangDexianABSTRACTPurpose:ToobservetheclinicaltherapeuticeffectofTangbiningcombinedwithcobaltammoniumtreatingthediabeticperipheralneuropathyandrelativeadvantageofsimple

4、westernmedicine.Method:TheprospectiverandomizedmethodwouldbeadaptedindividingsixtyDPNpatientsintotwogroups,oneistreatmentgroup(Tangbiningcombinedwithcobaltammoniuminjection500ugeachtime),theotheriscontrolgroup(cobaltammoniuminjection500ugeachtime),eachgroup

5、hasthirtypatientswhocorrespondwiththediagnosisstandard.Thencomparedwithclinicalsymptomscoreandnerveconductionvelocityofbothsidesaftereightweekstreatmentwithstatisticalmethod.Result:Twogroupsofpatientsinclinicalsymptomsandnerveconductionvelocityhaveimproved.

6、Thetotaleffectiverateis63.33%intreatmentgroup,whileits83.33%incontrolgroup.Tangbiningcombinedwithwesternmedicineismuchbetterthanthecontrolgroupintheclinicalsymptomandthenerveconductionvelocity.Conclusion:TangbiningcombinedwithcobaltammoniumhasgreateffectonD

7、PNofqiandyindeficiencyandbloodstasisandalsowellknowforitssafety.ThiswouldprovidenewideaintreatingwithDPNofTCM.Keywords:DiabeticPeripheralNeuropathy;Tangbining;cobaltammoniuminjection；TraditionalChineseMedicinecombinedwithWesternMedicine目录引言.................

8、..................................................................................................................1临床研究..................................................................................