调肝扶脾法治疗腹泻型肠易激综合征的临床研究

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1、提要目的：运用调肝扶脾法治疗腹泻型肠易激综合征，中医泄泻辨证为肝郁脾虚型。通过观察其临床疗效，评价调肝扶脾法治疗腹泻型肠易激综合征的临床疗效性和可行性。方法:(1)选取符合纳入标准的患者60例，所有病例均符合罗马Ⅲ诊断标准，中医辨证为肝郁脾虚型。随机分为试验组30例，对照组30例。两组患者年龄、性别、病程、及治疗前中医症状总积分上无明显差异，具有可比性(P>0.05)。(2)试验组服用导师的经验方调肝扶脾方水煎服。对照组给予口服中成药固肠止泻丸，每次5克，每日2次。试验组及对照组均以连续用药4周为一疗程，共用2个疗程。分别比较两组治疗前后症状总积分、治疗后证候综合疗效、治疗前后各临床主要症状积

2、分作出综合评定。结果：1.试验组30例中，临床治愈12例，显效9例，有效6例，无效3例，治愈率加显效率占70.00%，总有效率90.00%；对照组30例中，临床治愈2例，显效9例，有效10例，无效9例，治愈率加显效率占36.67%，总有效率60.00%。两组比较治愈率加显效率差异有显著性(P<0.01)，总有效率差异有统计学意义(P<0.05)。提示试验组在中医证候的改善程度方面明显优于对照组。2.治疗后两组总积分比较差异有统计学意义(P<0.05)。提示两组均能明显改善泄泻之肝郁脾虚型IBS的症状，两组相比较，试验组疗效明显优于对照组。3.两组病例在治疗过程中均未见明显不良反应。结论:调肝扶

3、脾法在消除或改善腹泻型肠易激综合征患者主要临床症状上具有良好疗效且安全无毒副作用。关键词调肝扶脾法腹泻型肠易激综合征临床研究ClincalstudiesonthecureofdiarrheaIBSthroughadjustingliverandsupportingspleenSpeciality：ClinicalStudyofTCMAuthor：YuDanjieTutor：WangWeimingAbstractObjective:Diarrhea-predominantirritablebowelsyndromewastreatedbythemethodofadjustingliverands

4、upportingspleen,andsyndromedifferentiationofdiarrheawasthehepaticstagnationandspleendeficiencytype.Theclinicalefficacyandfeasibilityofthemethodofadjustingliverandsupportingspleenforthecureofdiarrhea-predominantirritablebowelsyndromewerewereanalyzedthroughobservingtheclinicalefficacy.Method:(1)60pati

5、entswerechosenbyadoptionstandardsandallwereuptothediagnosticstandardofRomeIII,andsyndromedifferentiationwasthehepaticstagnationandspleendeficiencytype.60patientswererandomlydividedintotwogroups,30patientsasthetreatmentgroupand30patientsasthecontrolgroup.Therewasnosignificantdifferenceamongtheage,sex

6、,courseofdiseaseandthetotalaccumulativemarkofTCMsymptomsbeforetreatmentsintwogroups,andtherehadcomparability(P>0.05)(2)Thetreatmentgroupwasgivenexperiencedprescriptionofadjustingliverandsupportingspleen(decoctedinwater)bytutor,whilethecontrolgroupwasgivenChinesepatentmedicinesuchasGuchangZhixiePills

7、inoralwith5gramseverytime,twotimesaday.Thetreatmentgroupandthecontrolgroupwerebothgivenmedicinefortwocourses,fourweekscontributingonecourse.Basedonaboveexamination,thetotalaccumulativemarkofsymptomsbe