pga、pla纤维与纺织结构肌腱支架的降解性能分析

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1、东华大学硕士学位论文PGA、PLA纤维及纺织结构肌腿支架的降解性能研究STUDYONTHEDEGRADATIONOFPGA、PLAFIBERSANDTEXTILESTRUCTURESCAFFOLDFORTENDONLV少了T况口ABSTRACTThedegradationrateandchangesofthemechaniealProPertiesbeforeandafterdegradationofthedegradablebiomediealmaterialshaveasignificantimPactontheirmedieal

2、aPPlieations.Therequirementsofthebiomediealartificialscaffoldmaybestatedasfollows:exeellentmeehanicalProPerties，goodbioeomPatibilityaswellasanapProPriatedegradationratetomatehtheaPPlieationtime.Onlywiththesecanmeettheneedsoforganizationalreconstruetionandrestorationoffu

3、nction.Inthefieldofdegradablebiomediealmaterials，PGAandPLAaretwoimPortantsynthctiePolymermaterials.TheybothhavelargerapPlieationsathomeandabroadatPresent.PGAhasabetterbiocomPatibility.It15suitableforeelladhesionandProliferation，buttherateofdegradationinthebody15toofast，

4、theneworganizationeannotaffordtothebodyloadwhenPGAhadlosttheirmechaniealProPerties.PLAhasaslowerdegradationratetomeetthemechaniesrequestoftheseaffoldinthebody，butdue东华大学硕士学位论文PGA、PLA纤维及纺织结构肌键支架的降解性能研究tothePoorbiocomPatibility，it15notconducivetoeelladhesionandProliferati

5、on.Asaresult，thewayofPhysiealblendingorchemicalcoPol卿eringdifferentProPortionsofPLAandPGAtogetabettermaterial，whichhasanaPProPriatedegradationratetomatchthesPeedoforganizationalreconstruetionandalsocanmeettherequirementsofthestrengthandbiocomPatibility，hasbeeometheProbl

6、emsandhotsPotsoftheresearehinthefieldofbio一degradablemediealmaterial.Inthisarticle，thebasicProPertiesofboththePolylaeticaeid(pLA)andpolyglycolicacid(pGA)fibersbymeltsPinningweremeasured.Inordertodiseusstheefl七ctofdifferentstatesofaggregationuPonthedegradationProeess，fou

7、rkindsofbraidedsutureswithdifferenteomPonents(PGA/PLA=6/O，4/2，2/4，O/6)，bundleandbraidedofPGAfibersindifferentstatesofaggregationwerestudiedbytestingtheweight1055，thermalProPerties，surfaeemorphologyandmechaniealProPerties.Atthesametime，theauthorselectedtherawmaterialsofd

8、ifferentviseositiesforsPinningwithdifl七rentProeessParameterstostudytheintrinsieviseosity，drawingtemPeratureand