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1、提要目的：通过对山东中医药大学附属医院213例恶性肿瘤住院患者情况的分析，探讨恶性肿瘤患者肿瘤相关性抑郁、焦虑的发病情况及影响因素，为临床治疗提供借鉴。方法：对住院患者进行问卷式临床调查，采用SPSS17.0软件进行数据统计，分析恶性肿瘤住院患者肿瘤相关性抑郁、焦虑的发病情况及各因素对抑郁、焦虑发病率的影响，找出中医证型和肿瘤相关性抑郁、焦虑发病的相关性及影响患者肿瘤相关性抑郁、焦虑发病的独立危险因素。结果：肿瘤相关性抑郁发病率为46%，其中中度抑郁发病率为18.3%，未发现重度抑郁者；肿瘤相关性焦虑发病率为16.4%，其中中度焦虑发病率为6.
2、6%，未发现重度焦虑者。肿瘤相关性抑郁与肿瘤发病部位、肿瘤家族史、居住地无关（P＞0.05），与性别、年龄、肿瘤分期、中医辨证分型、慢性癌痛、KPS评分、化疗方案种类、治疗副作用、知情情况、费用负担方式、文化程度、收入相关（P＜0.05），其中性别、中医辨证分型、肿瘤分期、既往化疗史、知情情况、慢性持续性疼痛、KPS评分等7个为独立危险因素。中医辨证分型中气郁化火、肝气郁结、痰气郁结发病率依次为95%、92.1%、61.2%。结论：肿瘤相关性抑郁、焦虑临床发病率较高，对女性、中晚期、有多次化疗史、KPS评分低、伴慢性癌痛者，应重视其心理状况，及
3、时发现并诊断治疗，以提高患者生存质量。关键词肿瘤相关性抑郁、焦虑；发病率；影响因素Clinicalinvestigationtheincidenceofcancer-relateddepression,anxietyandtherelatedfactorsSpecialty：ClinicalinternalmedicineofTCM&WesternmedicineStudent：SunhaiyanTutor：Prof.QiyuanfuAbstractObjective:Byanalyzingthe213casesofmalignanttumor
4、sfromtheAffiliatedHospitalofShandongUniversityofTraditionalChineseMedicinehospitalizedpatients,toexploretheincidenceofmalignanttumorsinpatientswithcancer-relateddepression,anxietyandaffecttheincidenceofrelevantfactorstoprovideareferenceforclinicaltreatment.Methods:Inpatients
5、areinvestigatedbyquestionnaire,andSPSS17.0statisticalsoftwarefordataanalysis,analysisincidenceandthefactorsontheincidenceofcancer-relateddepressionandanxietyofhospitalizedpatients,andidentifyTCMsyndromeandcancer-relateddepressionandanxiety,andidentifyindependentriskfactorsfo
6、rpatientswithcancer-relateddepression,anxiety.Results:Theincidenceofcancer-relateddepressionis46%,andmoderatecancer-relateddepressionincidencerateis18.3%,andhavenotfoundseverecancer-relateddepression;cancer-relatedanxietyincidenceis16.4%,moderatecancer-relatedanxietyis6.6%,h
7、avenotfindseverecancer-relatedanxiety.Cancerincidence,familyhistoryofcancer,placeofresidence,educationhasnothingtodowithcancer-relateddepression.Gender,age,tumorstage,TCMsyndrome,chronicpain,KPSscore,thetypeofchemotherapytreatmentsideeffects,informed,cost-burdenway,incomeand
8、othervariablesontheincidenceofcancer-relateddepressionwasstatisticallysigni
