微刺激促排卵方案在ivf卵巢低反应患者中的应用

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1、AbstractApplicationofmild—stimulateovulationinIVFpatients‘■■●wim0VarlanPoorresponseSupervisor：Prof．删unSunTheThirdAffiliatedHospitalofZhengZhouUniversityZhengzhouHenan450052Intheprocessofcontrolledovarianhyperstimulationofinvitrofertilization-embryotra

2、nsfer(IVF硼，approximately9％-24％ofpatientsoeellrpoorovarianresponse．Forthispartpatients，gonadotropindrugsareinsensitivetothemforvariousreasons，resultinginmoregonadotropindosageusedintheprocessofovulation，longtimeovulation，slowfolliclegrowth，lessoocyte，p

3、ooroocytequalityandlowThereforeforthepatientswhomayoccurpoorovarianresponseintheprocessofCOH，ch-oosingwhichschemepromotingovulationisnotonlytoimprovetheovarianreaction，butalsoincreasethenumberofoocyteandthepregnancyrate．Thisproblembecomesthecurrenthot

4、researchfieldofassistedreproductive．Inthepasttenyears，theresearcherstrydifferentpromotingovulationschemetothesepatients．Recentlymild—stimulationpromotingovulationschemehasbegantograduallyappliedtothesepatients．Mild—stimulateovulationisnotinpituitarydo

5、wn-regulationcase,takingdirectlyovulationinductiondrugssuchasClomiphene，letrozole，ere，withorwithoutaddingasmallamountofGnIVF—ET．Atpresent，theapplicationofthepromotingovulationschemeinpatientswithpoorovarianresponsegainsincreasingly．IVAbstractObjective

6、Toexploretheapplicationofmild—stimulateovulationinvitrofertilizationandembryotransfer(IVF-ET)amongpatientswithpoorovarianresponse．MethodsSelect130patients，atotalof141cycles，from2010．5to2012．5inthethirdaffiliatedhospitalofZhengzhouuniversity,whoaccepte

7、dIVF／ICSlwithpoorovarianresponse,infertilityduetotubalfactor,husbandwithlessweakspermsicknessandSOonandaccord、析movarianlowreactionstandard．Accordingtothedrugusing,casesaredividedintothreegroups：GroupA(1etrozolegroup)：Atotalof40cycles，andGroupB(clomiph

8、enecitrategroup)：Atotalof41cycles，GroupC(shortprotocolgroup)：Atotalof60cycles．Usingchemiluminescencetechnologytodetermineallpatients’basicendocrineandLH、P、E2valuesonhCGinjectionday．Threegroupsofpatientswerecomparedwithage，bodymassindex(BMI)，du