血管内支架治疗颅内复杂动脉瘤的临床研究

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1、授予单位代码10089学号或申请号20123092HebeiMedicalUniversity硕士学位论文专业学位血管内支架治疗颅内复杂动脉瘤的临床研究研究生：董鹏飞导师：王立群教授专业：外科学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任

2、。研究生签名表赠如导师签章：二级学院领导盖章:河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：导师签章：im年，月》。曰目录中文摘要·············································································1英文摘要·····················································

3、························4英文缩写·············································································8研究论文血管内支架治疗颅内复杂动脉瘤的临床研究前言·············································································9材料与方法····································································9结果········

4、·····································································14附图·············································································16附表·············································································34讨论···························································

5、··················36结论·············································································41参考文献·······································································42综述支架在颅内动脉瘤治疗中的新进展···································45致谢····························································

6、·······················54个人简历·············································································55中文摘要支架在颅内复杂动脉瘤治疗中的相关研究摘要目的：颅内动脉瘤是造成自发性蛛网膜下腔出血的首位病因，占85%，是神经外科常见疾病。AN破裂出血后脑血管痉挛、再出血与急性脑积水是危及生命的并发症，具有较高的死亡率，可高达25%-60%，开颅夹闭动脉瘤是疗效确切的经典治疗方法，但其有明显不足：创伤大、难度大及风险高等不足。近年来弹簧圈栓塞治疗以其微创的特点得到飞速发展，大

7、量研究也证实了其疗效确切，然而对于复杂动脉瘤，单纯弹簧圈难以完全栓塞或根本无法治疗，随着血管内治疗技术的进步，其支架辅助弹簧圈栓塞技术血管内治疗颅内动脉瘤适应症越来越广，效果也更加肯定。相关研究表明，血管内治疗的死亡率和致残率明显小于手术夹闭，这与血管内治疗新技术、新材料的发展密不可分。现在越来越多的医师和患者选择这种微创的、疗效可靠的治疗方法。回顾分析我科采用支架治疗的颅内复杂动脉瘤病例，评估应用血管内支架治疗颅内动脉瘤的安全性与疗效。方法：收集河北医科大学附属第二