甲苯磺酸索拉非尼片的研制

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1、授予单位代码１００８９ｒ１学城＃前１４２０２？阿＾钟Ａ多ＨｅｂｅｉＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ硕±学位论文在职科学学位甲苯磯酸索拉非尼片的研制学位申请人：宋禅导师：曹德英教授专业：药剂学二级学院；药学院２０１５年１０月ｆ河北医科大学学位论文使用授权及知识产权归属承巧由本人独立完成。）的指导下，本学位论文在导师（或指导小组果学所本学位论文研究所获得的研究成，其知识产权归河北医科大进行交流。凡发表有

2、、公开和使用。河北医科大学有权对本学位论文论文一署名为单位河北医科大学，与学位论文主要内容相关的，第试验材料、原始麗、申攤专利等知识产权均归河北医科大学所。有，承担相应法律责任。否则研究生签名：导师签章啼歡弓马河化医科大学研究生学位论文独创性声明研究成果，本论文是在导师指导下进行的研究工作及取得的邑经除了文中特别加Ｗ标注和致谢等内容外，文中不包含其他人发表或撰果，指导教师对此进行了审定。本论文由本人写的研究成。独立撰写，文责自负―导师签章：研究生签名；斗棒义

3、（束遂年月曰！戶Ｉ目录中文摘要··············································································1英文摘要··············································································5研究论文甲苯磺酸索拉非尼片的研制引言·····················································

4、·························7第一部分甲苯磺酸索拉非尼片的制备前言··············································································8材料与方法·····································································8结果···················································

5、···························19附图··············································································20附表··············································································22讨论························································

6、······················29小结··············································································29参考文献········································································29第二部分甲苯磺酸索拉非尼片的质量研究前言···············································

7、·······························30材料与方法·····································································30结果··············································································32附图··························································

8、····················38附表··············································································38讨论··············································································46小结·······················································