青年食管癌临床病理特征分析与预后分析

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1、授予单位代码10089学号或申请号20123190V妗(E钭大杳HebeiMedicalUniversity硕士学位论文专业学位青年食管癌临床病理特征分析与预后分析研究生：李立哲导师：刘庆熠教授专业：外科学2015年3月J可北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研宄成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。

2、否则，承担相应法律贵任。研宄生签名：导师签章:二级学院领导盖章：1年4月1日河北医科大学研究生学位论文独创性声明本论文是、在导师指导下进行的研宄工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人己经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研宄生签名:导师签章：冬(P?年2月：：7日目录中文摘要·············································································1英文摘要······················

3、·······················································4研究论文青年食管癌临床病理特征分析及预后分析前言·············································································8材料与方法····································································9结果················································

4、·····························11附图·············································································15附表·············································································20讨论·············································································22结论······

5、·······································································27参考文献·······································································27综述青年食管癌的临床特点··················································29致谢··································································

6、·················38个人简历·············································································39中文摘要青年食管癌的临床特征对比分析及预后分析摘要目的：食管癌是一种常见的消化道恶性肿瘤，全球每年有48万新发食管癌病例，其发病率占全部恶性肿瘤中的第8位。食管癌的发病率具有明显的地域性差异，其发病率和死亡率在不同的国家和地区有很大差异。我国是食管癌高发地区之一，食管癌发病总数占全世界的46.6%，全国平均每年有15万人死于食管癌。近年来食管癌的发病率有所下

7、降，但发病年龄趋于年轻化，其发病率占全部食管癌发病率的5%左右。食管癌的发病人群多以中老年（大于40岁）为主，青年患者（40岁以下包括40岁）较少。关于食管癌的临床特点我们已经有了比较全面的了解，但是对于青年食管癌而言，其临床特征及预后情况并不为我们所了解。本研究拟对原发性青年食管癌的临床特征进行回顾性研究与分析，以期了解其临床特征及预后的影响因素。方法：本文整理总结河北医科大学第四医院2002年到2009年期间收治的行手术治疗并术后病理确诊的38例青年食管癌患者的完整临床病例资料并将其作为研究组与随机抽取同期手术治疗并术后病理确诊的60例中年年食管癌患者的

8、临床资料做对比分析。研究组:误诊有19例。有吸烟史患