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1、上海交通大学硕士学位论文持续性房颤环肺静脉消融术后复发相关因素分析姓名：董佳霖申请学位级别：硕士专业：内科学（心血管病）指导教师：刘旭20080401结论持续性房颤CPVA+CFAEs术后患者，最大P波时程是早晚期复发的独立预测因素，器质性心脏病是晚期复发的独立预测因素。左房大小、年龄和病程时间对于持续性房颤消融术后复发有一定参考作用，但不是绝对禁忌，应结合临床情况及其他指标综合考虑。P波离散度、左室射血分数、性别和BMI与持续性房颤消融术后复发无关。关键词：心房颤动，肺静脉，环肺静脉消融术，复发，预测PREDIC
2、TORSOFPRESISTATRIALFIBRILLATIONRECURRENCEAFTERCIRCUMFERENTIALPULMONARYVEINABLATIONABSTRACTObjectiveTodeterminethepredictorsofearlyorlaterecurrenceafterCPVA+CFEAbylasso.MethodsDataisbasedonthepresistatrialfibrillationpatients(n=89)afterCPVA+CFEA.Accordingtothei
3、rclinical,electrophysiologymanifestation,aswellasthedataoffollow-upafteroperation,dividethedataintorecurrencegroupandnon-recurrencegroup,ttestwereusedtofindtheirdifference,multivariateanalyseswereusedtofindouttherelationshipbetweenAFrecurrencewiththemultiplefa
4、ctors.Results29cases(32%)showedATa,including19cases(21.3%)ofAF.29cases(32.6%)showedlaterecurrence.MultivariateanalysesshowedthatmaximalPwavedurationwastheindependentpredictorforearlyrecurrence（P=0.03,OR1.024,CI1.002-1.046）.However,structualheartdisease（P=0.006
5、,OR4.849,CI1.582-14.866）andmaximalPwaveduration（P=0.002,OR1.048,CI1.017-1.080）aretheindependentpredictorsforlaterecurrence.ConclusionTopresistatrialfibrillationpatients,maximalPwavedurationisindependentpredictorofearlyandlaterecurrence,structualheartdiseaseisi
6、ndependentpredictoroflaterecurrence.LAD,age,timeofatrialfibrillationhaverelationshiptorecurrence,butnoabsoluteness.KEYWORDS：cardiology,atrialfibrillation,pulmonaryvein,circumferentialpulmonaryveinablation,recurrence,predictor符号说明1CPVA环肺静脉消融术2LSPV-leftsuperiorp
7、ulmonaryvein左上肺静脉3LIPV-leftinferiorpulmonaryvein左下肺静脉4RPV-rightpulmonaryvein右肺静脉5BMI-体重指数6CFAEs-complexfractionatedatrialelectrograms复杂碎裂心房电图7CTI-Inferior-VenaCaval-TricuspidValveIsthmus三尖瓣峡部8ICL-IntervalConfidenceLevel间期可信水平9SCI-ShortestComplexInterval最短复杂碎裂电
8、位间10CFEA-complexfractionatedelectrogramablation碎裂电位消融11AT-atrialtachycardia房性心动过速12ATa-atrialtachyarrhymia房性快速性心律失常上海交通大学学位论文原创性声明本人郑重声明：所呈交的学位论文，是本人在导师的指导下，独立进行研究工作所取得的成果。除文中已经注明引
