资源描述：
《prostate cancer imaging in diagnosis》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、DavidSherGillianLieberman,MDMarch2002ProstateCancer:ImaginginDiagnosisandTreatmentDavidSher,HarvardMedicalSchoolIIIGillianLieberman,MDDavidSherGillianLieberman,MDIntroduction•Theprostateglandisawalnut-sizedexocrineglandthatsurroundstheurethrabetweenthebladderneckandthegenitourinarymemb
2、rane•Itssecretionsprimarilyfunctioninsemengelation,coagulationandliquefaction–Prostaticproteinsarealsoinvolvedincoating/uncoatingthespermatozoaandininteractionswithcervicalmucus•Diseaseprocessesrangefrombenign(benignprostatichyperplasia,BPH)toinflammatory(prostatitis)tomalignant(prosta
3、tecancer)2DavidSherGillianLieberman,MDAnatomicRelationshipsAxialSagittalCoronalGray’sAnatomyOnline.http://www.bartleby.com/107/CoakleyFV,HricakH.RadiologicAnatomyoftheProstate.RadiologicClinicsNA;38(1):15-30.3DavidSherGillianLieberman,MDProstateAnatomyLobarAnatomyZonalAnatomyCoakleyFV,
4、HricakH.RadiologicAnatomyoftheProstate.RadiologicClinicsNA;38(1):15-30.4DavidSherGillianLieberman,MDProstateCancer:PresentationProstateCancerDetectedEarlyDetectedLateElevatedPSAAbnormalDREOutflowObstructionMetastaticDiseaseProstateCancerFalsePositiveProstateCancerProstateCancerIntrinsi
5、cOrganPathologyBPHAcuteChronicBPHOtherMetastaticDiseaseExtra-ProstaticGrowthBladderDiseaseBiopsyBPHUrethral/PenileDiseaseTURPChronicProstatitisMalignantExtensionAcuteUrinaryRetentionAcuteProstatitisEjaculation5DavidSherGillianLieberman,MDProstateCancer:Basics•Prostatecanceristhemostcom
6、monlydiagnosedcancerinmen(~200,000cases/year)–Lifetimeriskofdevelopingprostatecancer:16%–Riskofdyingfromprostatecancer:3.4%•Itisthe2ndleadingcauseofcancer-relatedmortalityamongmen(~40,000deaths/year)•Ingeneral,themalignancyisslow-growing,althoughtheprognosisvariesdrasticallyaccordingto
7、stage•PSAscreeninghasundoubtedlydetectedmorecancers,withadebatablesurvivalbenefit•Riskfactorsincludeolderage,blackrace(RR1.5),familyhistory(1stdegreerelativedoublesrisk)•Radiologyplaysavitalroleindiagnosisandtreatment6DavidSherGillianLieberman,MDDiagnosis•Diagnosisismadeby•Classicall
