资源描述：
《A presurgical psychosocial intervention for breast cancer patients》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、JournalofPsychosomaticResearch48(2000)187±194Apresurgicalpsychosocialinterventionforbreastcancerpatients:psychologicaldistressandtheimmuneresponseMarkR.Larson*,PaulR.Duberstein,NancyL.Talbot,ChristopherCaldwell,JanA.MoynihanCenterforPsychoneuroimmunologyResearch,Un
2、iversityofRochesterMedicalCenter,300CrittendenBoulevard,Rochester,NY14642,USAAbstractObjective:Thepresentstudyevaluatedthefeasibilityandgery;and(3)atpostsurgery.Results:Examinationoftheim-potentialimmunologicalbene®tofapresurgicalinterventionmunologicaldatarevealed
3、evidenceofsuppressionofforbreastcancerpatients.Methods:Forty-onenewlydiag-interferon-g(IFN-g)inthecontrolgroupovertime,butnotnosedbreastcancerpatientswererandomizedintocontrolintheinterventiongroup.Secondary®ndingsrelatedtopsy-(standardcare)andinterventiongroups.In
4、additiontostan-chologicalassessmentgenerallyparalleledtheIFN-gresults.dardcare,interventiongroupmembersreceivedatwo-sessionConclusion:Therelevanceandapplicabilityofthese®ndingspsychosocialintervention.Bloodwasdrawnatthreetime-tofuturebreastcancerinterventionresearc
5、hisdetailed.points:(1)atpreintervention;(2)atpostintervention/presur-Ó2000ElsevierScienceInc.Allrightsreserved.Keywords:Breastcancer;Intervention;Immunity;Interferon-g;Naturalkillercells;FeasibilityIntroductionmunesuppressionmayberelatedtopsychologicaldis-tress[22,
6、23].Stress-relatedimmunesuppressionmayWomendiagnosedwithbreastcanceroftenexperi-evencontinueintothepostsurgicalperiod.Forexample,enceahostofnegativeemotions,includinganger,fear,Andersenandcolleagues[24]concludedthathigherandhopelessness[1±4].Acrossavarietyofstressf
7、ullevelsofstresssigni®cantlypredictedlowerNKcelllysissituations,negativeemotionalresponsesareoftenparal-anddiminishedNKcellresponsetorecombinantIFN-gleledbypotentiallydeleteriousalterationsoftheim-invitro.muneresponse[5±8].Forexample,theexperienceofAssumingthatpsyc
8、hologicaldistressandimmunestresshasbeenlinkedtodepressedimmunefunction,suppressionarerelated,interventionsdesignedtohelpincludingreducednaturalki
