枸杞降脂方治疗非酒精性脂肪肝合并高尿酸血症临床观察

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1、枸杞降脂方治疗非酒精性脂肪肝合并高尿酸血症临床观察作者：张玉喜，王龙成,马晓瑞，王铁武,樊瑞军单位：宁夏口治区人民医院，宁夏银川750021宁夏口治区第四人民医院，宁夏银川750021【摘要】目的观察枸杞降脂方治疗非酒精性脂肪性肝病(NAFLD)合并高尿酸血症(HUA)的有效性。方法将80例患者分为两组，治疗组40例,予以中药枸杞降脂方，水煎服；对照组40例，予以口服血脂康胶囊。8周为1个疗程，连续治疗2个疗程。观察两组患者服药前后临床症耳犬；血清ALT、AST、γ-GT^TC、TG、UA值；B超检查。结果治疗组的总体疗效明显优于对照组(P<0.01)；治疗组在B超改

2、善及临床症状改善方血优于对照组(P<0.05)；治疗组血淸尿酸明显降低(PV0.01),对照组无明显降低(P>0.05),治疗组在降低血清尿酸方而优于对照组(P<0.05)；两组治疗后血清ALT、AST、γ-GT>TC、TG值均明显降低(P<0.05),但组间差异无统计学意义(P>0.05)o结论枸杞降脂方是治疗NAFLD合并HUA的有效复方制剂。【关键词】非酒耕性脂肪肝；高尿酸血症；中医药疗法；临床疗效Clinicalobservationontreatmentofnon-alcoholicfattyliverdiseasecomplicatedwithhyperu

3、ricaemiabywolfberryregulatingliquidprescriptionZHANGYu-xi,WANGLong-cheng,MAXiao-rui,etal.(NingxiaPeople'sHospital,Yinchuan750021,China)[Abstract]ObjectiveToobservetheeffectsofwolfberryregulatingliquidprescriptionwhichcouldtreatnon-alcoholicfattyliverdisease(NAFLD)complicatedwithhyperuricaemia

4、(HUA).Methods80patientsweredivideinto2groups:Intreatmentgroup,40patientswhichwereappliedtowolfberryregulatingliquidprescriptionbyherbaldecoction,andincontrolgroup,40patientswhichwereappliedtoxuezhikangcapsulesbyperosand8weekswasacourseoftreatment.Twogroupswerecontinuouslytreatedtwocourseoftre

5、atment.TherapeuticevaluationwastoresearchclinicalsymptomsandALT,AST,γ・GT,TC,TGandUAinsenimandB-ultrasonicexaminationaboutbeforeandaftertreatment.ResultsThewholemedicaleffectsoftreatmentgroupwasbetterthanthatincontrolgroups(P<0.01);clinicalsymptomsimprovementandresultsofB-ultrasonicexami

6、nationoftreatmentgroupwasbetterthanthatincontrolgroup(P<0.05);serumuricacidleveloftreatmentgroupwasbetterthanthatincontrolgroup(P<0.05);ALT,AST,γ-GT,TCandTGinserumoftwogroupswerealldecreaseed(PV0.05),buttherewasnosignificantdifferenceintwogroups(P>0.05).ConclusionWoltberryregulatingliqu

7、idprescriptionisaeffectivecompoundpreparationswhichcantreatnon-alcoholicfattyliverdiseasecombinedwithhyperuricaemia.[Keywords]Non-alcoholicfattyliverdisease;Hyperuricaemia;TherapyoftraditionalChinesemedicine;Clinicaleffects近年來，随着社会经济发展和人民牛活水平