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1、CHINESECOMMUNITYDOCTORS论著·临床论坛小儿肺炎支原体感染的诊断与治疗王芳436000湖北省鄂州市妇幼保健院儿科doi:10.3969/j.issn.1007-614x.2017.12.28摘要目的：探讨小儿肺炎支原体感染的诊断方法及治疗效果。方法：收治支原体肺炎患儿80例，随机分成观察组和对照组，各40例。对照组3岁以下口服阿奇霉素10mg/kg，1次/d，服3d停4d，2周1个疗程；3岁以上给予阿奇霉素注射液10mg/kg+200mL5%葡萄糖注射液静脉滴注，1次/d，连续
2、治疗6d，改为口服，2周1个疗程。观察组在对照组的基础上联合应用氨溴索注射液7.5mg+50mL5%葡萄糖注射液静脉滴注，2次/d，连续治疗7d。结果：流行病学特点、临床症状、实验室检查和胸片检查是诊断小儿支原体肺炎的重要措施依据。经过治疗，观察组患者的退热时间、咳喘消失时间、肺部啰音消失时间、肺部炎症消失时间明显短于对照组(P＜0.05)，观察组患者用力肺活量(FVC)、第1秒最大呼气量(FEV1)、最大呼气流速(PEF)、用力呼气25%流速(MEF25)、用力呼气50%流速(MEF50)均明显
3、高于对照组(P＜0.05)，观察组总有效率明显高于对照组(P＜0.05)。结论：流行病学特点、临床症状、实验室检查和胸片检查是诊断小儿支原体肺炎的重要措施依据。阿奇霉素联合氨溴索治疗小儿支原体肺炎效果显著。关键词阿奇霉素；小儿；支原体肺炎；氨溴索DiagnosisandtreatmentofmycoplasmapneumoniaeinfectioninchildrenWangFangDepartmentofPaediatrics,EzhouCityMaternalandChildHealthHos
4、pitalofHubeiProvince436000AbstractObjective:Toexplorethediagnosismethodandtreatmenteffectofmycoplasmapneumoniaeinfectioninchildren.Methods:80childrenwithmycoplasmapneumoniaeinfectionwereselected.Theywererandomlydividedintotheobservationgroupandthecont
5、rolgroupwith40casesineach.Inthecontrolgroup,thechildrenunder3yearsoldweregivenoralazithromycin10mg/kg,1timeoneday,eating3daysandstopped4days,2weeksof1course;thechildrenabove3yearsoldweregivenazithromycininjection10mg/kgand200mL5%glucoseinjectionintrav
6、enousinfusion,1timeoneday,continuoustreatmentfor6days,changedtooral,2weeksof1course.Onthebasisofthecontrolgroup,theobservationgroupwasgivenambroxolhydrochlorideinjection7.5mgand50mL5%glucoseinjectionintravenousinfusion,2timesoneday,continuoustreatment
7、for7days.Results:Epidemiologicalcharacteristics,clinicalsymptoms,laboratorytestsandchestX-rayexaminationwereimportantmeasuresforthediagnosisofmycoplasmapneumoniaeinchildren.Aftertreatment,theantifebriletime,coughdisappearedtime,pulmonaryralesdisappear
8、edtimeandpulmonaryinflammationdisappearedtimeoftheobservationgroupweresignificantlyshorterthanthoseofthecontrolgroup(P＜0.05).Theforcedvitalcapacity(FVC),firstsecondmaximalexpiratoryvolume(FEV1),maximalexpiratoryflowrate(PEF),forcedexpiratory25
