老年糖尿病并发周围神经功能紊乱的临床观察.doc

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1、老年糖尿病并发周围神经功能紊乱的临床观察［摘要］目的观察并分析老年糖尿病并发周围神经紊乱的临床治疗效果。方法选取该院在2013年10月一2015年10月收治的150例老年糖尿病足并发周围神经病变的患者作为研究对象，将所有患者按照随机法划分为观察组和对照组，每组75例。对照组患者单纯采用前列地尔进行•治疗，观察组患者采用前列地尔配合a-硫辛酸注射液进行治疗，对两组患者的治疗效果进行观察并做比较。结果两组患者干预前后的踝肱指数、空腹血糖、餐后2hlfll糖、糖化血红蛋白相较均有差异，但观察组患者的干预后与干预前相比，差异有统计学意义（PC0.05）；对比两组患

2、者的多伦多临床神经病变（TCSS）评分，差异有统计学意义（P〈0.05）。结论临床上对于老年糖尿病并发周围神经病变的患者,采用前列地尔联合a-硫辛酸注射液进行治疗，效果更好，能够提高患者的恢复，值得推广使用。［关键词］老年糖尿病；周围神经功能紊乱；前列地尔［中图分类号］R4［文献标识码］A［文章编号］1672-4062（2016）05（b）-0003-02ClinicalObservationonElderlyDiabetesComplicatedby卩eripheralNerveFunctionDisorderZHANGMingDepartmentofE

3、mergency,TheAffiliatedHospitalofNorthChinaUniversityofScience&Technology,Tangshan,HebeiProvince,063000China[Abstract]ObjectiveToobserveandanalyzetheclinicaltreatmenteffectofelderlydiabetescomplicatedbyperipheralnervefunctiondisorder.Methods150casesofelderlypa/tientswithdiabetescom

4、plicatedbyperipheralnervefunctiondisorderadmittedandtreatedinourhospitalfromOctober2013toOctober2015wereselectedastheresearchobjectandrandomlydividedintotwogroupswith75casesineach,thecontrolgroupweretreatedwithsimplealprostadil,theobservationgroupweretreatedwithalprostadilandalpha

5、thiocticacidinjection,thetreatment,effectsofthetwogroupswereobservedandcompared.ResultsThereweredifferencesintheankle-brachialindex,fastingblood-glucose,2hpostprandialbloodglucose?andglycosjdatedhemoglobinbeforeandafterinterventionbetweenthetwogroups,butthedifferencesintheobservat

6、iongroupafterinterventionweremoreobviousthanthosebeforeinierventionwithstatisticalsignificance（P〈0.05）,thedifferenceintheTorontoclinicalnervefunctiondisorderscoringbetweenthetwogroupswasobviouswithstatisticalsignificance（P〈0.05）.ConclusionTheeffectofalprostadilandalphathiocticacid

7、injectionintreatmentofelderlypatientswithdiabetescomplicatedbyperipheralnervefunctiondisorderinclinicisbetter,whichcanimprovetherecoveryofpatients,anditisworthpromotionandapplication.[Keywords]Elderlydiabetes；Peripheralnervefunctiondisorder；Alprostadil临床上糖尿病是一种严重的疾病，这种疾病对患者的正常生活带来

8、较大影响，而且容易引发各类并发症，其屮糖尿病周围神经病变便是其屮一