资源描述：
《英文外刊原版文章1.doc》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、1EthicistsandmedicalexpertsintheU.S.saythattheuseofgeneeditingtomakebabiesresistanttoHIVinfectionisasteptoofar―andcouldbeastepbackforgeneticscience.NewsbrokeearlyMondaymorningthatChinesescientistHeJiankuialteredthegeneticcodeoftwoembryostomakethemresistanttoHIV,andthentrans
2、ferredthemtoawomanwholatergavebirthtotwogirls―twinsisters.Whilehisclaimshaveyettobeverified,HesaysthatonebabyhastwosetsofthealteredCCR5gene,whichhehopeswillpreventHIVfrombeingabletoenterhercellsifsheweretoevercomeincontactwiththevirus.Theotherbabyonlyappearstohaveonesetofal
3、teredCCR5genes,whichmaynotprotecthercompletelyfromHIVinfectionbutmayextendherlifeifsheweretobecomeinfected.WhileHeistryingtopresenthisfindingsasaboonfortheHIVcommunity,researchersandbioethicistsintheU.S.saytheannouncementhasleftthembaffledandconcerned.HIVresearchersareinter
4、estedingeneediting,butnotthewayHedidit,saidPaulVolberding,co-directoroftheUniversityofCalifornia,SanFranciscoGladstoneCenterforAIDSResearch.Wedon’tyetknowtherisks,andherehealthy,uninfectedpeoplearebeingused.PaulVolberding,co-directoroftheUniversityofCalifornia,SanFranciscoG
5、ladstoneCenterforAIDSResearch“I’mveryinterestedinwaysthatgeneeditingmightbeemployedinattemptingtocureHIVinfection,butitsusetopreventinfectionseemsseriouslymisguided,”Volberdingsaid.“HIVinfectioncaneasilybepreventedwithantiretroviraldrugs.”Andgiventhattreatmentsandtherapiesa
6、lreadyexisttopreventHIVtransmissionfromparenttochild,hefindsit“verytroubling”thatscientistswouldputthesebabiesthroughtheseuntestedmethods.“Wedon’tyetknowtherisks,andherehealthy,uninfectedpeoplearebeingused,”Volberdingsaid.Someoftheserisksincludetheyet-unknownconsequencesofp
7、ermanentlyalteringagene,whichwouldthengetpassedontosubsequentgenerations.Forexample,TheAssociatedPress,whichbrokethestory,notesthatpeoplewithabnormalCCR5genesaremorepronetodyingfromthefluandcontractingWestNileVirus.2AtthefirstChinaInternationalImportExpo(CIIE)heldinShanghai
8、,aneye-catchingnumber--US$40trillion--hasstirredupwavesinparticipants'discussions.
