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《注射用丁二磺酸腺苷蛋氨酸结合丁二磺酸腺苷蛋氨酸肠溶片治疗肝内胆汁淤积的疗效观察.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、注射用丁二磺酸腺昔蛋氨酸结合丁二磺酸腺昔蛋氨酸月为;容片:台疗月干内月旦汁淤积的疗效观察【摘耍】目的观察注射用丁二磺酸腺廿蛋氨酸结合丁二磺酸腺廿蛋氨酸肠溶片治疗肝内胆汁淤积的临床效果。方法90例肝内胆汁淤积患者，将其随机分为三组，每组30例。单用注射用丁二殒酸腺昔蛋氨酸为注射组，单用丁二磺酸腺背蛋氨酸肠溶片为口服组，两药同时应用为结合组，对比并分析各组的治疗效果。结果治疗后所有患者血清总胆红素(TBIL)、结合胆红素(DBIL)、谷丙转氨酶(ALT)和谷草转氨酶(AST)水平均明显下降(P〈0・05),结合组下降最为显著，其与注射组及口服组比较，差异有统
2、计学意义(P〈0.05)；结合组治疗后临床疗效优于注射组和口服组(P〈0・05)。结论注射用丁二磺酸腺背蛋氨酸结合丁二磺酸腺昔蛋氨酸肠溶片治疗肝内胆汁淤积的效果要优于单一用药，值得在临床中广泛应用。【关键词】丁二磺酸腺苜蛋氨酸；肝内胆汁淤积；疗效D0I：10.14163/j.cnki.ll-5547/r.2015.17.019Observationofcurativeeffectbyademetionine1,4一butanedisulfonateforinjectioncombinedwithademetionine1,4-butanedisulfon
3、ateenteric-coatedtabletinthetreatmentofintrahepaticcholestasisYANGYin-mei,CIIENQin-shou,LIXiong.GaozhouCityPeoplesHospital,Gaozhou525200,China[Abstract]ObjectiveToobservetheclinicaleffectofademetionine1,4-butanedisulfonateforinjectioncombinedwithademet.ionine1,4-butanedisulfonate
4、enteric-coatedtabletinthetreatmentofintrahepaticcholestasis.MethodsAtotalof90patientswithintrahepaticcholestasiswererandomlydividedintothreegroups,with30casesineachgroup.Injectiongroupreceivedsingletreatmentbyademetionine1,4-butanedisulfonateforinjection,oraladministrationgroupre
5、ceivedademetionine1,4一butanedisulfonateenteric-coatedtabletfortreatment,andcombinedgroupreceivedcombinedtreatmentbythetwodrugs・Curativeeffectsofthreegroupswerecomparedandanalyzed.ResultsAftertreatment,allpatientshaddecreasedlevelsoftotalbilirubin(TBIL),directbilirubin(DBIL),alani
6、neaminotransferase(ALT),andaspartateaminotransferase(AST)(P<0.05)・Thecombinedgrouphadthemosthugedecrease,anditsdifferencewithinjectiongroupandoraladministrationgrouphadsta/tisticalsignificance(卩〈0.05).Thecombinedgroupalsohadbetterclinicaleffectaftertreatment,thantheinjectiongroup
7、andtheoraladministrationgroup(卩〈0.05)•ConclusionCombinationofademetionine1,4-butanedisulfonateforinjectionandademetionine1,4~butanedisulfonateenteric-coatedtablet,providesbettereffectintreatingintrahepaticcholestasisthansingledrugtreatment・Thismethodisworthyofwidelyclinicalapplic
8、ation.[Keywords]Ademetionine1,4-butanedi
