聚六亚甲基双胍盐酸盐的杀菌活性及现场空气消毒效果观察.pdf

《聚六亚甲基双胍盐酸盐的杀菌活性及现场空气消毒效果观察.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、·1016·ChineseJournalofDisinfection2013;30(11)【论著】聚六亚甲基双胍盐酸盐的杀菌活性及现场空气消毒效果观察1112221张先菊，苏裕心，任哲，魏秋华，宋世佩，陈晨，邓致荣，张文福(武警总医院，北京100039;1军事医学科学院疾病预防控制所;2第二炮兵防疫队)摘要目的观察聚六亚甲基双胍盐酸盐的杀菌活性和现场空气消毒效果。方法采用悬液定量杀菌试验和空气消毒现场试验方法，对盐酸聚六亚甲基双胍杀菌效果和现场空气消毒效果进行了观察。结果用浓度为128mg/L盐酸聚六亚甲基双胍消毒液对悬液内金黄色

2、葡萄球菌作用3.0min，杀灭对数值＞5.0;用256mg/L的该消毒液对悬液内大肠杆菌作用4.5min，杀灭对数值＞5.0;用1024mg/L的该消毒液对悬液内白色念珠菌作用6.0min，3杀灭对数值＞4.0。用浓度为2000mg/L的该消毒液以10ml/m用量进行气溶胶喷雾密闭作用30min，对室内空气中自然菌的消除率＞90%。结论该盐酸聚六亚甲基双胍对细菌繁殖体和真菌都有较好的杀灭效果，对空气中自然菌也能达到很好的消毒效果。关键词聚六亚甲基双胍盐酸盐;消毒剂;杀菌效果;空气消毒中图分类号:Ｒ187.2文献标识码:A文章编号:

3、1001－7658(2013)11－1016－04EXPEＲIMENTALOBSEＲVATIONONBACTEＲICIDALACTIVITYANDFIELDDISINFEC-TIONEFFICACYOFINDOOＲAIＲBYPOLYHEXAMETHYLENEBIGUANIDINEHYDＲO-CHLOＲIDE11122ZHANGXian－Ju，SUYu－xin，ＲENZhe，WEIQiu－hua，SONGShi－pei，CHENChen，DENGZhi21－rong，ZHANGWen－fu(GeneralHospitalofChin

4、esePeople'sArmedPoliceForces，Beijing100039;1InstituteforDiseasePreventionandControl，AcademyofMilitaryMedicalSciences，Beijing100071;2EpidemicPreventionBrigadeoftheSecondArtilleryCorpsofPLA，China)AbstractObjectiveToexplorethegermicidalpropertiesandindoorairdecontaminati

5、onefficacyofpolyhexamethylenebiguanidinehydrochloride(PHMB·HCl)．MethodsSuspensionquantitativegermicidaltestandairfieldairdisinfectiontestwereusedtoevaluatethebactericidalactivityandfielddisinfectioneffectofthePHMBHCl．ＲesultsTheaveragekillinglogarithmvaluesofStaphyloco

6、ccusaureusinsuspensionexposedto128mg/LPHMBHClsolutionfor3.0minwas＞5.0．AndwhichofEscherichiacoliexposedto256mg/LPHMB·HClsolutionfor4.5minwas＞5.0，whilethatofCandidaalbicansexposedto1024mg/LPHMB·HClsolutionfor6.0minwas＞4.0．Itwasobservedinexperimentthat3aerosolsprayof2000

7、mg/LPHMB·HClsolutionatadosageof10ml/mfor30mininaclosedroomeliminatedover90%ofnaturalbacteriainair．ConclusionsThePHMBHClcankillvegetativeformsofbacteriaandCandidaalbicanseffectively，andcaneffectivelyeliminateover90%ofnaturalbacteriainindoorairwithaerosolsprayof2000mg/L

8、PHMBHClsolution．Keywordspolyhexamethylenebiguanidinehydrochloride;disinfectant;germicidalefficacy;airdisinfection聚六亚甲基双胍盐酸盐(