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1、尤瑞克林治疗轻中度急性脑梗死临床疗效观察［摘要］目的：探讨尤瑞克林对轻、中度急性脑梗死的临床效用。方法：将40例轻、中度急性脑梗死的患者随机分为治疗组和对照组。治疗组20例采用尤瑞克林治疗。对照组20例米用丹参治疗。对治疗前、后进行临床神经功能缺损程度的评定和疗效评分。测定治疗前、后平均血流速度(V)、平均血流量(Q)和外周血管阻力(R),全血黏度、血小板聚集率、红细胞压积。结果：治疗组有效率明显高于对照组(PV0.05)。治疗组用药后2周与用药前比较，治疗组与对照组治疗后比较：平均血流速度(V)和平均血流量(Q)均明显增加(P<0.05
2、),外周血管阻力(R)均明显降低(PV0.05)；用药后2周，治疗组和对照组全血高切、低切黏度和血小板聚集率、红细胞压积均无显著性差异(P>0.05)。结论：尤瑞克林治疗轻、中度急性脑梗死安全有效。［关键词］轻、中度急性脑梗死；尤瑞克林；临床疗效［中图分类号］R743.33［文献标识码］B［文章编号］1673-7210(2010)11(c)-034-03ClinicalcurativeeffectobservationonHumanUrinaryKallidinogenaseintreatmentoflightly,themoderatea
3、cutecerebralinfarctionLIUYuting,CHENXiaofei(DepartmentofNeurology,ShanxiCardiovascularHospital,Taiyuan030024,China)[Abstact]Objective：ToobserveclinicalcurativeeffectofHumanUrinaryKallidinogenasetreatslightly,themoderateacutecerebralinfarction.Methods：40exampleslight,themod
4、erateacutecerebralinfarctionpatientweredividedintothetreatmentgroupandthecontrolgroup,randomly.Thetreatmentgroup(n二20)weretreatedwithHumanUrinaryKallidinogenase,thecontrolgroup(n二20)werewithSalviamiltiorrhiza・Beforeandaftertreatment,evaluatedtheclinicalnervefunctiondamaged
5、egreetheionandcurativeeffectgrading.Determinateaveragebloodstreamspeed(V),theaveragebloodstreammeasures(Q)andcircumferencebloodvesselresistance(R),thewholebloodviscosity,thebloodplateletaccumulationrate,theredbloodcellpressestheproductbeforeandafterthetreatment・Results：Tre
6、atmentgroupeffectivenesswashigherthanthecontrolgroupobviously(P<0.05).Beforethemedicationcomparedwithafterthemedication：thetreatmentgroupapplieddrugslater2weekandbeforethemedicationwerecompared,afterthetreatmentgroupandthecontrolgroupwerecompared：averagebloodstreamspeed(V)
7、andtheaveragebloodstreammeasure(Q)increasedobviously(P<0.05),circumferencebloodvesselresistance(R)reducedobviously(P<0.05)；thetreatmentgroupandthecontrolgroupapplieddrugslater2weekwholebloodviscosity(higherandlower)andthebloodplateletaccumulationrate,theredbloodcellpressur
8、eaccumulateswerenotremarkablechanges(P>0.05),non-statisticsdifference・Conclusion：HumanUri
