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《B超联合CT下行射频消融术治疗原发性肝癌的临床效果观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、中国综合临床2014年7月第3O卷第7期ClinicalMedicineofChina,July2014,Vo1.30,No.7·68l··论著·B超联合CT下行射频消融术治疗原发性肝癌的临床效果观察张世玺【摘要】目的探讨在B超联合CT下和在CT下行射频消融术(RFA)治疗原发性肝癌的临床效果。方法原发性肝癌患者82例,均行经肝动脉化疗栓塞术治疗,术后1周41例患者在B超联合CT下行RFA治疗(治疗组),余41例在CT下行RFA治疗(对照组),观察两组患者的肿瘤体积缩小率和0.5、1、2年生存率。结果治疗组和对照组肿瘤体积缩小总有效率分别为95.12%(39/41)
2、和80.49%(33/41),组间比较差异有统计学意义(x2=5.33,P<0.05)。治疗组治疗后0.5、1、2年生存率分别为100%(41/41)、82.9%(34/41)和73.2%(30/41);对照组分别为100%(41/41)、70.7%(29/41)和51.2%(21/41),两组治疗1、2年生存率比较差异均有统计学意义()(2值分别为3.96、5.07,P均<0.05)。结论在B超联合CT下行RFA治疗原发性肝癌的临床效果明显优于CT下行RFA治疗组。【关键词】原发性肝癌;经导管肝动脉化疗栓塞术;射频消融术;B超;CTTheclinicalefect
3、ofradiofrequencycatheterablationguidingbyBultrasoundcombined、thCTinthetreatmentofprimarylivercancerZhangShixiInfectiousDiseaseDepartment,theFirstPeoplesHospitalofShangqiu,Shangqiu476JO0,China【Abstract】ObjectiveToexploretheclinicaleffectofradiofrequencycatheterablation(RFCA)guidingbyBul
4、trasoundcombinedwithCTontreatingprimaryhepaticcarcinoma.MethodsEighty—twopatientswithprimarylivercancerweretreatedwithtranscatheterarterialchemoembolizationtherapy.Oneweekaftertheoperation,41patientsweretreatedwithRFCAguidingbyBultrasoundcombinedwithRFAtherapyandservedastreatmentgroup.
5、Another41casesweregivenRFAtreatmentguidingbyCTascontrolgroup.Theindicesincludingtumorshrinkagerate,survivalrateof0.5,1and2years.ResultsThetumorshrinkageandtotaleffectiveratesinthetreatmentandcontrolgroupwere95.12%(39/41)and80.49%(33/41),andtherewasstatisticallysignificantdifferencebetw
6、eenthetwogroups(x=5.33,P<0.05).Aftertreatment,thesurvivalratesof0.5,1and2yearsintreatmentgroupwere100%(41/41),82.9%(34/41)and73.2%(30/41),andthatofthecontrolgroupwere100%(41/41),70.7%(29/41)and51.2%(21/41).Therewassignificantdifferencesbetweengroupsintermsofthesurvivalratesof1and2years
7、(x:3.96,5.07,P<0.05).ConclusionThecurativeeffectofRFAguidingbyBultrasoundcombinedwithCTissignificantlysuperiortothatguidingbyCT.【Keywords】Primaryhepatocellularcarcinoma;Transcathetera~erialchemoembolization;Radiofrequeneyablation;Bultrasound;CT原发性肝癌目前仍是恶性程度较高、死亡率较位近年来呈逐渐下降趋势。TACE治疗原发
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