欢迎来到天天文库
浏览记录
ID:55061336
大小:168.46 KB
页数:2页
时间:2020-05-08
《惠州地区204例儿童慢性荨麻疹血清特异性IgE抗体检测及过敏原分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、临京医学工程2014年6月第21卷第6期·8o7··论著·(调查统计)惠州地区204例儿童慢性荨麻疹血清特异性IgE抗体检测及过敏原分析房晶晶,陈辉,吴海娟,谢梅珍(广东省惠州市皮肤病医院,广东惠州516001)【摘要】目的分析惠州地区儿童慢性荨麻疹患者血清总IgE抗体及特异性IgE抗体水平,了解过敏原分布情况。方法入选2012年1月至2013年12月儿童慢性荨麻疹204例,应用IgE抗体特异性过敏原检测试剂盒(ELISA法)检测血清IS特异性抗体。结果204例慢性荨麻疹患儿中总lgE阳性198例,阳性率为97.1%,19
2、6例患儿检测出过敏原,阳性率为96.1%,其中食入组主要为蛋黄46例(22.5%),牛奶42例(20.6%),蟹、虾4O例(19.6%);吸入组主要为花粉、屋尘、尘螨76例(37.3%),蟑螂52例(25.5%)、猫狗毛发皮屑44例(21.6%)。食入组及吸入组的阳性率无显著性差异(P>0.o5)。不同特异性过敏原在各阳性级别均有分布,总rgE均为(+++)级或(++)级。结论多数儿童慢性荨麻疹患者同时出现多种过敏原,其中主要食入因素有蛋黄、牛奶、蟹、虾,主要吸入因素主要为花粉、尘螨、蟑螂、猫狗毛发皮屑。【关键词】儿童;慢
3、性荨麻疹;IgE抗体;过敏原中图分类号:R392.8文献标识码:Adoi:10.3969/j.issn.1674—4659.2014.06.0807DetectionofSerumSpecificIgEAntibodyandAnalysisofAllergenin204ChildrenwithChromeUrticariainHuizhouFANGJinxing,CHENHui,UHaijuan,XIEMe'hen(14uizhouDermatologyHospital,Huizhou516001,China)【Abstr
4、act]ObjectiveToanalyzetheleveloftotalIgEantibodyandthespecificIgEantibodyinserumofchildrenwithchronicurticariainHuizhouandunderstandthedistributionofallergen.Methods204childrenwithchronicurticariainourhospitalfromJanuary2012toDecember2013werecollected.IgEantibodys
5、pecificallergendetectionkit(ELISA)wasappliedtodetectthelevelofserumspecificIgEantibody.ResultsI98positivecasesoftotalIgEweredetectedfrom204childrenwithchronicurticaria,andthepositiveratewas97.1%.Allergensweredetectedin196casesandthepositiveratewas96.1%;thefood—int
6、akegroupincluded46cases(22.5%)ofeggyolk,42cases(20.6%)ofmilk,40cases(19.6%)ofcrabsandshrimp;theinhalationgroupincluded76cases(37-3%)ofpollenanddustmites,52cases(25.5%)ofcockroach,44cases(21.6%)ofcatanddogdander;therewasnosignificantdifferencebetweenfood—intakegrou
7、pandinhalationgrouponpositiverate(P>O.05).DifferentspecificallergensweredistributedineverypositivelevelandtotalIgEwas(+++)or(++)leve1.ConclusionsMostchildrenwithchronicurticariaarepositivewithseveralallergenssimultaneously.Themajorfoodallergenincludedeggyolk,milk,
8、crabs,shrimp,andthemajorinhalationallergenswerepollen,dustmites,cockroach,anddanderofcatanddog.[Keywords]Children;Chronicurticaria;IgEantibody;Allergen荨
此文档下载收益归作者所有