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1、lungcancerWhatisLungCancer?BeginswhencellsinthelunggrowoutofcontrolandformatumorEtiologyandpathogenesisCigarettesmokingOtherfactorsincludeairpollutionsNowadaysItisreportedthattuberculosisisassociatedwiththeincidenceoflungcancerClassificationsAccordingtoanatomy:(1)Centrallung(2)peripherallungcancer
2、Accordingtohistologicclassification:Smallcelllungcancer(SCLC)andNon-smallcelllungcancer(NSCLC).NSCLCincludesSquamouscellcarcinoma,largecellcarcinoma,adenocarcinoma,adenosquamouscarcinoma.Smallcelllungcancer(SCLC)Oat-cellcarcinomaSCLCgrowsveryrapidlyandisveryaggressive.Soonaftertheoriginalcellbecom
3、escancerous,itquicklymultipliestoformatumor.ThesecellsswiftlyspreadtodistantsitesinthebodySCLCbelongsinagroupoftumorsderivedfromneuroendocrinecellsthatareresponsiblefortheproductionandsecretionofspecificpeptideproduct.theymayrelatedtoparaneoplasticsyndrome.Cellsareovalorvaguelyspindle-shaped,haves
4、cantcytoplasmSquamouscellcarcinomathemostfrequentformofthetumor(30-50percentofallcasesbronchialepitheliumandgrowthinsituItisrelatedtocigarettesmokingCavitationcanoccureinthedistaltotheobstructingmassCentrallocationIntercellularbridgesandcellularpleomorphismsquamouscellcarcinomausuallyoccursnearthe
5、bronchi,thetumorcancausecough(sometimesacoughthatistingedwithblood),shortnessofbreath,wheezing,andpneumoniaintheareabetweenthetumorandtheedgeofthelungitcausessymptomsearlyinthediseaseadenocarcinomaareasofscarringisassociatedwiththeoccurrenceofadenocarcinoma.Peripheraladenocarcinomasareusuallywell-
6、circumscribed,grey-whitemassesthatrarelycavitate.Itarisesfromthesubmucosalglands,locatedinperipheralairwaysandalveoliFemalelargecellcarcinomalargenuclei,prominentnucleoli,abundantcytoplsmausuallylocatedperipherallycanbequitelargeandnotinfrequentlycavitatetheSymptomsofLungCancerFatigue(tiredness)Co
7、ughShortnessofbreathChestpainLossofappetiteCoughingupphlegmHemoptysis(coughingupblood)Ifcancerhasspread,symptomsincludebonepain,difficultybreathing,abdominalpain,headache,weakness,andconfusionDuetoprimarylesions:
