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1、红霉素序贯阿奇霉素与单纯阿奇霉素治疗儿童支原体肺炎的疗效比较(安徽省儿童医院安徽合肥230001)【】目的：分析研究红霉素序贯阿奇霉素与单纯阿奇霉素治疗儿童支原体肺炎的疗效，探讨儿童支原体肺炎新的更有效的治疗方法。方法：选取54例患儿符合诊断标准的支原体肺炎，随机分为红霉素序贯阿奇霉素组(A组)和单纯阿奇霉素组(B)两组，A组30例采用红霉素30mg/d，分2次静脉滴入，连用3天，改用阿奇霉素10mg/d，静脉滴入5天，停4天，以静滴量再口服3天。B组24例采用阿奇霉素10mg/d,静脉滴入5天，停4天，以静滴量再门服3天停药。结果：红霉素序贯阿奇霉素组的痊愈率70%,明显高于
2、阿奇霉素组58.3%(P<0.05),症状、体征消失较快。结论：治疗儿童支原体肺炎时应首先选择红霉素对支原体血症进行控制，然后再用新一代人环内酯类抗生素阿奇霉素序贯治疗，比开始采用阿奇霉素的疗效好，显效快，有推广应用的价值。【关键词】阿奇霉素；红霉素序贯阿奇霉素；儿童支原体肺炎【】R720.5【】A【】2095-1752(2016)28-0015-02Comparativeeffectivenessoferythromycinsequentialazithromycinandpureazithromycintreatmentofmycoplasmapneumoniainc
3、hildrenLuSongjian.Children'sHospitalinAnhuiProvince,AnhuiProvince,Hefei230001,China【Abstract】ObjectiveAnalysisoferythromycinsequentialazithromycinandpureefficacyofazithromycintreatmentofchildrenmycoplasmapneumoniaandexplorenewchildmycoplasmapneumoniamoreeffectivetreatments.MethodsSelection54
4、caseswererandomlydividedintoerythromycinsequentialazithromycingroup(groupA)andpureazithromycingroup(B)inthetwogroups,Agroupof30cases,usingerythromycin30mg/·d,intravenousdripintothepoints2times,stay3days,toswitchtoazithromycin10mg/·d,intravenousdripintothefivedays,fourdays,withs
5、taticdropsoforal3daysagain.24casesofgroupBwithazithromycin,10mg/·d,intravenousdripintothefivedays,fourdays,withstaticdropvolumeoral3daysagain.ResultsErythromycinsequentialazithromycingroupcureratewas70%,significantlyhigherthanthe58.3%ofazithromycingroup(P<0.05).ConclusionsTreatment
6、ofchildrenmycoplasmapneumonia,shouldfirstchooseerythromycinonmycoplasmadiseasecontrol,andthenwithanewgenerationoflargeringlactoneclassantibioticazithromycinsequentialtreatment,isbetterthanbegantoadoptthecurativeeffectofazithromycin,takeseffectquickly,hasthevalueofpopularizationandapplication
7、.【Keywords］Azithromycin;Erythromycinsequentialazithromycin;Mycoplasmapneumoniainchildren支原体肺炎(MPP)属于儿童社区获得性肺炎中的常见疾病，苏发病率在近年来有上升趋势。在传统的治疗方法上，多采用红霉素静滴或口服，但治疗不彻底，主要原因是治疗周期长，不良反应较多等，操作相对简便，0前采用较多的是新一代大环内酯类阿奇霉素治疗，静滴或口服，每日只需给药1次，患病儿童的依从性好，进入细胞及组织的浓度高，而细胞
