老年高血压病患者动态血压与颈动脉粥样硬化程度及左室肥厚的关系

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1、万方数据生垦堕盎堡鳇盘查垫!!生；旦筮!!鲞笙!塑垦!i!』g丛旦!型!坠：墅!型!翌!Q!!!∑!!：!兰：堕Q：!老年高血压病患者动态血压与颈动脉粥样硬化程度及左室肥厚的关系陆平，陈谊，王曹锋，成静，盛净(上海交通大学医学院附属第九人民医院老年病科，上海200011)·41··论著·[摘要】目的探讨老年高血压病患者动态血压参数对颈动脉内一中膜厚度及左室肥厚的影响。方法老年高血压病患者95例经颈动脉超声和超声心动图检查被分为颈动脉内膜增厚组(n=67例)和内膜正常组(n=28例)；左室肥厚组(凡=30例)和左室正常组(rt=65例)。测定并比较动态血压参数，血脂、血糖等生化指标。结果

2、(1)颈动脉内膜增厚组和内膜正常组的临床指标比较差异无统计学意义(P>0．05)；(2)颈动脉内膜增厚组和内膜正常组动态血压参数比较差异有统计学意义(P<0．05)；(3)左室肥厚组和左室正常组的临床指标比较差异无统计学意义(P>0．05)；(4)左室肥厚组和左室正常组的动态血压参数比较差异有统计学意义(P<0．05)。结论高血压病动态血压参数对颈动脉内一中膜增厚和左室肥厚有显著影响，可能参与其发病机制。[关键词]高血压；动脉粥样硬化；肥大，左心室；老年人中图分类号：R544．1文献标识码：ADOI：10．3969／J．issn．1672-6790．2011．01．014Relatio

3、nshipbetweenambulatorybloodpressureandcarotidarteryintia·mediathicknessandleftvent—cularhypertrophyinoldpatientswithhypertensionLUR增．CHENYi，WANGCao-feng，CHENJing，SHENGJing(DepamnemofGeriatrics，TheNinthPeople’sHospitalAffiliatedtoJiao％ngUniversity，SchoolofMedicine，Shanghai200011，China)Correspondi

4、ngauthor：SHENGJing，E·mail：shan百in960@163．corn[Abstract]ObjectiveToinvestigatetheinfluenceofambulatorybloodpressuremonitoring(ABPM)parame-ternoncarotidintima-mediathickness(IMT)andleftventrieularhypearophy(LVH)intheoldpatientswithhyperten·sion．MethodsThe95oldhypertensionpatientsunderwentcarotidar

5、teriesultrasoundexaminationsandechocardio-graphyandweredividedintoincreasedIMTgroup(n=67)，normalIMTgroup(n=28)，LVHgroup(n=30)andnor-malleftventriclegroup(n=65)．TheABPMexaminationwereperformedinallthepatients．Results(1)TherewerenosignifcantdifferencesinclinicalmanifestationsbetweentheIMTincreasea

6、ndnormalgroup．(2)TheparametersofABPMinIMTincreasegroupwerehigherthanthoseofnormalgroup(P<0．05)．(3)Therewerenosignificantdiffer-encesinclinicalmanifestationsbetweentheLVHgroupandnormalgroup．(4)TheparametersofABPMinLVHgroupwerehigherthanthoseinnormalgroup，whichweresignificantlydifferent(P<0．05)．Co

7、nclusionThereisasignifi-cantinfluenceofABPMparametersonIMTofcarotidarteryandLVH．ABPMparametersabnormalitymaybeinvolvedintheonsetofLVHand1MT．[Keywords]Hypertension；Atherosclerosis；Hypertrophy，leftventricular；Aged动态血压监测已广泛用于诊断