维持血液透析患者血清钙、磷、甲状旁腺激素水平及高通量滤器干预观察.pdf

《维持血液透析患者血清钙、磷、甲状旁腺激素水平及高通量滤器干预观察.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、目巨墓i刍E旦耋蔓墨鲞匿翅II旦!September，2014．．9，No．13·629·临床研究·维持血液透析患者血清钙、磷、甲状旁腺激素水平及高通量滤器干预观察芮海荣’林为民王银。邵宝香【摘要】目的改善慢性肾衰竭尿毒症维持血液透析患者钙、磷、甲状旁腺代谢紊乱。方法对解放军第451医院原有82例患者改用高通量滤器透析治疗3个月后，对照钙、磷、甲状旁腺素(iPTH)水平。所有患者B超检测甲状旁腺，并进一步分为增生、非增生2组对比此效果。结果高通量滤器透析患者血钙升高(t=-一4．786，P

2、P

3、pyusinghighfluxh~modialyzeronscrulncalcium,phosphorus，andintactparathyroidhor-moneinInaintona．1lcehomodialysispatientsRUIHai-rong,LINWei-min,WANGYin,SHAOBao-xiangHemodialysisCenter,The451PLAHospital,Xian710054,ChinaCorrespondingauthor．"RUIHai-rong,Email：446175645@qq．com[Abst

4、ract]ObjectiveToimprovetheabnormalchangesofcalciumandphosphonlsandintactparathy．roidhormone(iPTH)inmaintenancehemodialysis(MHD)patientsusinghighfluxhemodialyzer．MethodsInatotalof82MHDpatientsthehemodialyzerforhemodialysiswaschangedfromlowfluxhemodialyzertohighfluxhemodialyze

5、rfor3months．Serumcalcium，phosphorusandiPTHwerecomparedbeforeandafterusinghighfluxhemodialyzer．PatientswerefurtherdividedintoparathyroidhyperplasiagroupandnormalparathyroidgroupbasedonthefindingsfromDopplerultrasonography．Serumcalcium，phosphorusandiPTHwerefurthercomparedbetwe

6、enthetwogroups．ResultsAfterusinghighfluxhemodialyze~serumcalciumlevelsincreased(f一4．786，P<0．05)，andphosphorusandiPTHdecreased(f=2．341，P<0．05forphosphorus；f：2．937．P<0．05foriPTH)．Theseeffectsweremoreprominentinparathyroidhyperplasiagroupthaninnor—malparathyroidgroup(f=一3．583／-

7、3．207P=0．001／0．003forserumCa；=1．74／1．619，P=0．089／0．113forSelMrnP；t=2．408／1．830，P=-0．001／0．074forserumiPTH)．ConclusionHighfluxhemodialyzerwasbeRerthanlowfluxhemodialyzertoimproveserumcalciumandphosphorusandiPTHchangesinMHDpatients．[Keywords]Bloodpurification；Highfluxhemodialy

8、zer；Calcium；Phosphorus；Parathyroidhormone维持性血液透析是目前肾脏替代治疗最主要方2013年在解放军第451医