活性氧信号转导作用靶标及作用机制论文

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1、活性氧信号转导作用靶标及作用机制论文陈海英郭沈波，陈雪红，于文功，王春波，兰晓明【关键词】活性氧信号传导细胞凋亡外界刺激在信号传递过程中产生活性氧（ROS），而ROS又可以刺激信号通路，参与细胞信号转导过程。在细胞凋亡信号转导的过程中，ROS既可以作为外界诱因.freelBiophys,2004,423(1):66.［2］DITTMANNK,MAYERC,FEHRENBACHERB,etal.RadiationinducedepidermalgroportislinkedtoactivationofDNAdepende

2、ntproteinkinase［J］.JBiolChem,2005,280(35):31182.［3］BAREGAMIANN,SONGJ,.freeloxidativestressinducedapoptosis［J］.JSurgRes,2006,136(1):31.［4］HANY,SONSJ,AKHALAIAM,etal.Modulationofradiationinduceddisturbancesofantioxidantdefensesystemsbyginsan［J］.EvidBasedplementAlte

3、rnatMed,2005,2(4):529.［5］GAUSSKA,NELSONOVERTONLK,SIEMSENDANDN,LEFEBVREJ,LAPOINTEG,etal.Inhibitionofplateletactivatingfactorbiosynthesisbyadenosineandhistamineinhumanneutrophils:involvementofcPLA2alphaandreversalbylysoPAF［J］.JLeukocBiol,2006,79(5):1043.［7］VONMON

4、TFORTC,FERNAUNS,BEIERJI,etal.ExtracellulargenerationofhydrogenperoxideisresponsibleforactivationofEGFreceptorbyultravioletAradiation［J］.FreeRadicBiolMed,2006,41(9):1478.［8］KAMATHR,JIANGZ,SUNG,etal.cAblkinaseregulatescurcumininducedcelldeaththroughactivationofcJ

5、unNterminalkinase［J］.MolPharmacol,2007,71(1):61.［9］ZHOUY,,etal.SignaltransductionpathulatescSrcmediatedbigmitogenactivatedproteinkinase1(BMK1)andtheMEF2Csignalingpath,2002,277(11):9614.［12］VANLAETHEMA,NYSK,VANKELSTS,etal.Apoptosissignalregulatingkinase1connec

6、tsreactiveoxygenspeciestop38MAPKinducedmitochondrialapoptosisinUVBirradiatedhumankeratinocytes［J］.FreeRadicBiolMed,2006,41(9):1361.［13］于爽，郭沈波，严州萍，等.扇贝多肽对UVB损伤HaCaT细胞ERKs/MAPKs通路的影响［J］.齐鲁医学杂志,2006,21(3):189192.［14］BOONSTRAJ,POSTJA.Moleculareventsassociatedammali

7、ancells［J］.Gene,2004,337:1.［15］SAKURAIT,KANAYAMAM,SHIBATAT,etal.Ebselen,aselenoorganicantioxidant,asanelectrophile［J］.ChemResToxicol,2006,19(9):1196.［16］LICR,ZHOUZ,LINRX,etal.betasitosteroldecreasesirradiationinducedthymocyteearlydamagebyregulationoftheintracel

8、lularredoxbalanceandmaintenanceofmitochondrialmembranestability［J］.JCellBiochem,2007,102(3):748.［17］HONGH,CAOH,,KIMBC,etal.Effectsofheterologousexpress