异丙酚和七氟醚麻醉诱导对维库溴铵起效影响

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1、上海交通大学硕士毕业论文导引起了舒张压明显降低P<0.05于P1和P2组(P<0.01)　S组插管引起的心血管反应小结论　七氟醚吸入诱导循环功能平稳而且可以明显缩短维库溴铵的起效时间　关键词异丙酚七氟醚维库溴铵　　-5-上海交通大学硕士毕业论文THEEFFECTSOFANESTHESIAINDUCTIONWITHPROPOFOLORSEVOFLURANEONTHEONSETOFVECURONIUM　ABSTRACTObjectiveTocomparetheinductionqualityofintravenouspropofo

2、lwithinhalationalsevofluraneandtoinvestigatetheireffectsontheonsettimeofvecuronium.MethodsNintyASAI—IIpatients,agedfrom18to65years,undergoingselectivesurgerywithgeneralanesthesiawererandomizedintothreegroupsgroupP1P2andSGroupP1intravenousinductionwith1mg/kgpropofolgroupP2

3、intravenousinductionwith1.5mg/kgpropofolrespirationgroupS:inhalationof8%sevofluraneinvitalcapacityAllpatientsreceivedinravenousfentanyl4ìg/kgimmediatelybeforeinductionExcludedcriterionpatientswithseverecardiovascularpulmonaryhepaticandrenaldysfunctionspreoperativelywithn

4、euromusculardisorderspreoperativelyorwithmorbidoberityMechanomyographyoftheadductorpollicismusclewithsingletwitch(ST0.1Hz)stimulationwasusedtomonitorneuromuscular-6-上海交通大学硕士毕业论文functionduringanesthesiainductionAfterthepaientslostconsciousnessacontinuous0.1Hzsinglestimulu

5、swith0.2mssquarewaveandcurrentof50mAwasdeliveredtotheulnarnerveatthewrist.Theevokedresponseoftheadductorpollicismusclewasrecorded.Whenthetwitchresponsewasstabilizedvecuronium0.1mg/kgwasadministeredTimetolossofeyelashreflexhemodynamicchangesonsettimeofvecuroniumandcondition

6、oftrachealintubationwererecordedResultsThetimetolossofeyelashreflexingroupS54.40±15.77sandgroupP261.92±11.96swassignificantlyshorterthanthatingroupP190.76±22.52sP<0.01TherewasnodifferencebetweenthoseingroupP2andgroupSTheonsettimeofvecuroniumingroupS110.40±23.10swassigni

7、ficantlyshorterthanthatingroupP1133.42±26.53sandthatingroupP2129.17±30.48sP<0.01ThetrachealintubationconditionwassimilarinthreegroupsTheinductiondepressedtheDBPingroupP2obviouslyP<0.05TrachealintubationcausedlessstressresponseingroupSthaningroupP1andP2P<0.01.Conclusion

8、Sevofluraneinductionhadastablecirculationcondition,andcanalsoaccelerateonsettimeof