资源描述:
《儿童过敏性紫癜336例临床分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、儿童过敏性紫癜336例临床分析【摘要】 目的:探讨儿童过敏性紫癜(HSP)的临床特点和治疗方案。方法:对2001年8月~2007年10月在本院住院的336例过敏性紫癜患儿的发病特点、临床表现、肾损害相关因素及预后等方面进行回顾性分析。结果:(1)2001~2007年每年的住院构成比依次为0.91%、1.12%、1.25%、1.28%、1.35%、1.48%及1.71%。(2)农村患儿213例,占63.39%。(3)诱因:感染因素216例(64.29%),进食特殊食物引起64例(19.04%),药物引起56例(16.67%)。(4)冬季发病148例(44.04%),春季发病130例(
2、38.69%)。(5)出现肾脏症状64例(19.04%),出现关节症状74例(22.02%),出现消化道症状70例(20.82%)。(6)血清IgA升高58例(17.26%),IgE升高102例(30.35%)。(7)预后:治愈276例(82.14%),好转32例(9.52%)。结论:(1)HSP患病率有逐年升高趋势;农村患儿发病较多;冬春季好发。(2)发病诱因仍以感染为第一位。(3)要重视儿童过敏性紫癜的多系统损害,如皮肤、关节、消化道、肾脏等。(4)发病与上呼吸道感染和机体免疫功能紊乱有关。【关键词】儿童紫癜过敏性临床特点 ClinicalAnalysisof336Childr
3、enwithHenochSchonleinPurpura10 ZHOUBin,LILida (XuzhouCentralHospitalofJiangsuProvince,JiangsuXuzhou221009,China) [Abstract]Objective:TostudytheclinicalcharacteristicsandtreatmentofchildrenwithHenochSchonleinpurpura(HSP).Methods:336caseswithHSPhospitalizedinourhospitalfromAugust,2001toOcto
4、ber,2007wereretrospectivelystudiedontheirpatternsofonset,clinicalmanifestations,correlatedfactorsofrenaldamageandoutcomes.Results:(1)TheconstituentratioofhospitalizationofHSPwas0.91%,1.12%,1.25%,1.28%,1.35%,1.48%and1.71%from2001to2007,respectively.(2)Amongthe336cases,213(63.39%)werefromruralare
5、a.(3)Inducingfactors:infections(216cases,64.29%),specialfood(64cases,19.04%)anddrugs(56cases,16.67%).(4)Winter148cases(44.04%),Spring130cases(38.69%).(5)Totally64cases(19.04%)presentedsymptomsofrenaldamage,74cases(22.02%)presentedsymptomsofjointsymptoms,70cases(20.82%)presentedsymptomsofgastroi
6、ntestinaltractsymptoms.(6)IncreasedIgAinserumin58cases(17.26%),increasedIgEin102cases(30.35%).(7)10Pprognosis:276(82.14%)caseswerecured,32cases(9.52%)weregreatlyimproved.Conclusions:(1)MorbidityofHSPincreasesyearbyyear.Morbidityishighinthechildrenfromruralareaandalsohighhighwheninwinterandsprin
7、g.(2)Themostimportantinducingfactorisinfection.(3)SpecialattentionshouldbepaidtomultisystemdamageinHSP,includingskin,joint,gastrointestinaltractandrenal.(4)HSPhasrelationwithupperrespiratorytractinfectionandfunctionaldisorderofim