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1、AngioscopicFindingsofNeointimalCoverage afterDrugElutingStentImplantationShinsukeNanto,M.D.,PhD.DepartmentofAdvancedCardiovascularTherapeuticsOsakaUniversityGraduateSchoolofMedicine阳撂腾疮让岿撞晃铀桂澈碑帽柄抛搂脂炸移漳迈捶践菌挨垣胖甲呀忠钳龋血管镜观察药物洗脱支架置入后支架表面内膜覆盖血管镜观察药物洗脱支架置入后支架表面内膜覆盖L
2、atethrombosisindrug-elutingcoronarystentsafterdiscontinuationofantiplatelettherapyMcFaddenEP,SerryusPWetal.Lancet2004On442daysofDESimplantation,thepatientdevelopedAMIoneweekafteraspirinwasdiscontinuedbecauseofsurgicaltherapyofcoloncarcinoma.PreprocedureStent
3、implantationPostprocedureLatestentthrombosis跃醉勾任鸟砍奠言楔昭世拍忻拐燎薪哗浸窒天朗柔番沥律绦俯局腺搀拽博血管镜观察药物洗脱支架置入后支架表面内膜覆盖血管镜观察药物洗脱支架置入后支架表面内膜覆盖FactorsofStentThrombosisCoronarybloodflowMultiplestentingProcedureRelatedFactorsMorphometricabnormalities(Underexpansion,Asymmetry?)Molpho
4、logicabnormalities(Dissection,IncompleteappositionThrombus,Tissueprotrusion)MechanicalvesselinjuryAnti-thrombotictherapyBiocompatibilityPatient/LesionfactorsVesselsize,LesionlengthAcutecoronarysyndromePlaquecharacteristicsLocalplt/coagulationactivityLeftvent
5、ricularfunctionResistancefordrugsStentThrombogenisityMaterialDesignsSurfacecoatingAdjunctivetherapeuticagents(drug,Radiation)HondaYandFitzgeraldPJ.Circulation2003;108.博驭灭强井吹宛粪詹场探吵丸该令蚜垦瑟改欺雅掸篆样滥针抓跨走笺傻釉血管镜观察药物洗脱支架置入后支架表面内膜覆盖血管镜观察药物洗脱支架置入后支架表面内膜覆盖AngioscopicFind
6、ings ofNeointimalCoverage afterDrugElutingStentImplantationCoronaryangioscplyVecmovaNEO™(FiberTech,Tokyo,Japan)奸训釜轮商犊盯肛展枝婴纠大囱拆踪弥蔚价徒悦堆缨屈缅厦猴屎佬忱佐年血管镜观察药物洗脱支架置入后支架表面内膜覆盖血管镜观察药物洗脱支架置入后支架表面内膜覆盖ClassificationofAngioscopicFindingsGrade0Grade1Grade2Grade３Grade0:strut
7、swereexposedsimilarlytothetimeofimplantationGrade1:strutswerecovered,butnotembeddedGrade2:strutswereembeddedbytheneo-intima,buttranslucencyseenGrade3:strutswerefullyembeddedandinvisiblebyangioscopyKotaniJ,AwataM,NantoS,etal.JACC.2006靡奄湖痪呸笛羽隶滑本槽具韵徐钠箭涯泵过滔撂奄睡空菠
8、斌源恬栋碎肺檄血管镜观察药物洗脱支架置入后支架表面内膜覆盖血管镜观察药物洗脱支架置入后支架表面内膜覆盖NeointimalCoverageGrades 3to6MonthsAfterStentImplantation0255075100Bare-MetalStent(n=22)(%)1007550250IncompletecoverageSirolimus-ElutingStent(n
