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页数:7页
时间:2018-10-19
《hcy和cysc在类风湿患者心脏损害中的临床研究》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、HCY和CysC在类风湿患者心脏损害中的临床研宄王贯宇1金锋2吴煜龙3宋新梅4王建国5通讯作者吴敬峰6张帆7田君红81.衡水市消防支队卫生队河北衡水053000;2.保定市法医医院骨科河北保定071000;3.保定市消防支队卫生队河北保定071000;4.保定市第二医院河北保定071000;5.河北大学附属医院河北保定071000;6.保定市第二医院河北保定071000;7.保定市第二医院河北保定071000;8.保定市蠡县县医院河北保定071000【摘要】目的:探讨HCY和CysC联合检测在类风湿关节炎患者合并心脏损害中的应用价值,为预测RA合并心脏损害及诊治提供参考
2、依据。方法:收集2010年至2013年间类风湿关节炎患者89例患者的血清,按有无心脏损害分为两组。结果:RA有心脏损害的发病率为37.1%,其血清HCY和CysC水平明显高于其它两组血清水平,经统计学分析,其差异具有统计学意义(p<0.05);而RA无心脏损害组和健康对照组比较,经统计学分析,其差异无统计学意义(p>0.05)o结论:检测RA患者血清HC丫和CysC水平,在预测心脏损害方面具有重要价值,为临床诊治提供重要参考,值得在临床推广应用。【关键词】同型半胱氨酸;胱抑素C;类风湿性关节炎;心脏损害【中图分类号】R799【文献标识码】B【文章编号】167
3、4-8999(2015)8-0281-02ClinicalresearchofHCYandCysCinthecardiacdamageofpatientswithrheumatoidWUYulongl,SONGXinmei2,WANGJianguo3,(1.LogisticsofOfficeofPublicSecurityFireControlDetachmentofBaoding,Baoding071000;2.TheSecondHospitalofBaoding'Baoding0710003.AffiliatedHospitalofHebeiUniversity,B
4、aoding071000)【Abstract】Objective:TostudytheapplicationvalueofHCYandCysCinthecardiacdamageofpatientswithrheumatoidandtoprovideareferencebasisforthepredictionofdiagnosisandtreatmentofRAwithcardiacdamage.Methods:Collectedtheserumof89patientsofrheumatoidarthritisbetween2010and2013,anddetecte
5、dthelevelofHCYandCysCinserumwithmachine.Theyweredividedintotwogroups,onegroupwaspatientsofcardiacdamagewithrheumatoidandtheothergroupwasnocardiacdamage.results:TheincidenceofRAwithcardiacdamageis37.1%.ThelevelofHCYandCysCincardiacdamageissignificantlyhigherthantheothertwogroups,Therewass
6、ignificantdifferencesincomparisonbetweenthegroupofcardiacdamageandtheothertwogroupstotheconcentrationofHCYandCysC(p<0.05);TherewasnosignificantdifferencesincomparisonbetweenthegroupofnocardiacdamagewithrheumatoidandthehealthygroupstotheconcentrationofHCYandCysC(p<0.05).Conclusion:T
7、herewasimportantvalueinpredictingcardiacdamagetodetectthelevelofHCYandCysCinpatientsofrheumatoid,whichdeservesfurtherclinicalapplication.【Keywords]hemocysteine;CystitisC;rheumatoidarthritis;cardiacdamage越来越多的证据显示类风湿性关节'炎(rheumatoidarthritis,RA)患者易合并心血管疾病[1】,其死亡原因是主要心脏损害[2
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