医院常见致病菌检测及其耐药情况分析

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1、医院常见致病菌检测及其耐药情况分析【摘要】目的了解高明从化地区临床常见致病菌的分布，分析相关致病菌的耐药现状，为临床治疗提供依据。方法1270株细菌培养阳性标本的病原菌，按美国临床实验室标准化委员会（NCCLS）标准进行药物敏感试验，根据药敏结果进行耐药情况分析。结果在检出的1270例病原菌中，革兰阳性菌828株，占检出菌株的65.2%，革兰阴性菌442株，占检出菌株的34.8%。革兰阳性菌以凝固酶阴性葡萄球菌为主，其次是金黄色葡萄球菌、粪肠球菌等；革兰阴性菌以大肠埃希菌为主，其次是奇异变形杆菌、肺炎克雷伯菌等；非发酵菌以铜绿假单胞菌为主，其次是洋

2、葱假单胞菌等。所有送检标本中，共检出真菌280株，成为生殖道送检标本中检出的重要病原菌。各种细菌对相应抗生素出现不同程度的耐药情况。结论条件致病菌成为越来越重要的病原菌，真菌感染有增多的趋势；掌握细菌耐药情况，合理规范使用抗生素，是感染治疗成功及延缓细菌出现耐药的关键。【关键词】微生物；感染；耐药性D0I：10.14163/j.cnki.11-5547/r.2015.17.001DetectionofcommonpathogenicbacteriainhospitalandanalysisofitsdrugresistanceWUHui-qiang

3、,DUWei-qiang.FoshanCityGaomingDistrictPeople^sHospital,Foshan528500，China[Abstract]ObjectiveTounderstanddistributionofcommonclinicalpathogenicbacteriainConghuadistrictofGaomingcity，andtoanalyzeitsdrugresistance,inordertoprovidereferenceforclinicaltreatment.MethodsDrugsensitivi

4、tytestwasappliedundernationalcommitteeforclinicallaboratorystandards(NCCLS)criterionfor1270strainsofpathogenicbacteriaaspositivesamples.Analysisofdrugresistancewasmadeaccordingtodrugsensitivitytestoutcomes.ResultsAmong1270detectedstrainsofpathogenicbacteria，therewere828strains

5、ofgram-positivebacterium，accountingfor65.2%，and442strainsofgram-negativebacterium,accountingfor34.8%.Gram-positivebacteriummainlyincludedcoagulasenegativestaphylococcus，followedbystaphylococcusaureusandenterococcusfaecalis.Gram-negativebacteriummainlyincludedescherichiacoli,fo

6、llowedbyproteusmirabilisandKlebsiellapneumonia.Non-fermentativebacterialmainlyincludedpseudomonasaeruginosa,followedbypseudomonascepacia.Thereweretotally280strainsoffungusamongthedetectionsamples,andthosefunguseswerethemainpathogenicbacteria.Differentbacteriahadvariousdrugresi

7、stancelevelsforcorrespondingantibiotics.ConclusionConditionedpathogenhasbecomemoreandmoreimportantaspathogenicbacteria,whilefungusalsohasincreasingtrend.Controlofdrugresistanceandrationalantibioticsusagearethekeysforsuccessfulinfectiontreatmentanddrugresistancesuspension.【Keyw

8、ords]Microorganism；Infection；Drugresistance