mferg联合oct对曲安奈德玻璃体腔注射治疗黄斑囊样水肿疗效评价

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1、AssessmentoftheeffectionofintravitrealinjectionoftriamcinoloneacetonideforcystoidsmacularedemabymultifocalelectroretinogramandopticalcoherencetomographyAbstraetObiective"Toevaluatethecorrelationbetweenfunctionandmorphologyofretinalchangesafterintravitrealtriamcinolon

2、eacetonide(IVTA)astreatmentforcystoidsmacularedemabymultifocalelectroretinogramandopticalcoherencetomography．Methods：Fifty．twocasesfifty-toweyeswerediagnosedwithcystoidsmacularedema(CME)byfluoresceinfundusangiogrpahy(FFA)andopticalcoherencetomographyfOCT)，randomlyass

3、ignedtogroupIVTA2mgorgroupⅣTA4mg．Bestcorrectvisualacuity(BCVA)，intraocularpressure(10P)，OCTandmultifocalelectroretinogram(mf-ERG)wereperformedonthepatientsbeforeandafterthetreatment1mo，3mo，6mo．FFAwereperformedonmepatientsbeforeandafterthetreatmentlmo、3mo．Statisticala

4、nalysis：ftestandanalysisofvariancewereusedtocomparetheeffectionofbeforeandafterIVTAintwogroups，comparativelyanalysedthedatesofmf-ERGandcentralfovealthickness(CFT)usingcorrelationtest．Results：PatientsingroupWTA2mgorgroupIVTA4mgfinishedthefollow-upperiodof1month，3month

5、，6monthaftertheinjection，BCVAandCFTwerebetterthanbaselineinbothgroups，whichhadnosignificantlydifferenceintwogroups(P>0．05)．mf-ERG：duringtheperiodoffollow．up，latenciesofN1wavechangedalittle．thelatenciesofP1wave，theamplitudedensitiesofNlandP1waveswereimproved．whichhadn

6、osignificantlydifferenceintwogroups(P>0．05)．LatenciesofN1andP1waveshadnocorrelationwithCFTbeforeandafterthetreatmentinbothN1wavehadnegativecorrelation、析thCFTgroups仔I>O．05)．Theamplitudedensitiesofafterthetreatment6monthsinbothgroups(P<0．05)．TheamplitudedensitiesofP1wa

7、vehadnegativecorrelationwithCFTbeforeandafterthetreatment1,6monthsin2mggroupfP

8、surehadnosignificantlydifferenceintwogroupsr胗0．05)．Conclusion：TheamplitudedenskiesofN1，therewerenoobviousdifferencebetweenP1wavehad