何学红教授学术思想总结及肾衰方治疗慢性肾脏病的临床与实验研究

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1、学校代号１０１６２学号２０１２１０１０００５０Ｌｉａｏｎｉ打ｇＵｎｉｖｅｒｓｉｔｙｏｆＴｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅＭｅｄｉｃｉｎｅ博±学位论文何学红教授学术思想总结及肾衰方治疗慢性肾脏病的临床与实验研究－位梁亮心学申请人＇’紅指导教师姓名巧学专业名称中度内科学’申请学位类型专业学位论文提交日期二〇—五年王月迂宁中医药大学学位论文独创性与真实性声明－本人郑浦声明：在巧呈交的学位论文中，本人经研巧所得的数据、原理、结论等切内容均真实，且经本人认真核对无误；我呈交的与

2、学位论文相关的资料（原始记录、照片、录條片、检查化验巧告单等）确为完獲的学位论文研充中的原始资料，本人没作任何修改：我呈交的学位论文是我本人在指导教师的指导下进行的研究工作及取得的研巧成果。除文中特别加Ｗ标注和致谢的地方外，论文中没有其他人已经发表或撰写过的研究成果，巧化人对巧完成此论义的帮助及对本研究所做的任何贡献均己在论文中作Ｔ明确说明并衆示谢意。？我呈交的学位论文及与该论文相关的资料若有不实之处，本人承担切相关责巧。学位论义作離名ｔ曰期；从５年月＾曰关于学位论文使用授权的声明本人完全了解迂宁中医药大学有关保留使

3、用学位论文的规定，同意学校保留或向国家有关部口机构送交论文的印刷版和电子版，允许被查阅和借顿。本人授权迈宁中医药大学可将本学位论文的全部或部分内容编入有关数据库巧行检索，可＾式采用影印、缩印或其他复印手段保存和汇编本学位论文。（保密论文在解密后应遵守此规定）举位论义作者签名举化论义导师豁务ｆ－：ｌ瑚；＞＜５年ｋ月。今辽宁中医药大学2015届博士学位论文目录一、摘要中文论著摘要·····························1英文论著摘要·····························5二、英文缩略语·····

4、························12三、正文论文一何学红教授学术思想及运用肾衰方加减治疗慢性肾脏病临床经验总结前言································15何学红教授学术思想渊源·······················16何学红教授对慢性肾脏病中医发病机理探微···············21何学红教授治疗慢性肾脏病的思辨特点·················28何学红教授运用经验方“肾衰方”治疗慢性肾脏病临证经验········34论文二以肾衰方加减为主一体化治疗慢性肾脏病3-4期脾肾气虚合并湿浊瘀血证12

5、6例回顾性病例观察前言································55资料与方法·····························55实验结果······························63讨论······························73结论·······························80论文三肾衰方缓解腺嘌呤致慢性肾衰大鼠肾纤维化机制的实验研究前言································81材料与方法·························

6、····81实验结果······························95讨论······························118结论·······························128四、本研究创新性的自我评价·······················129五、参考文献······························130六、附录综述·······························139附表·······························162辽宁中医药大学2015届博士

7、学位论文在学期间科研成绩··························197致谢·······························198个人简介······························199辽宁中医药大学2015届博士学位论文摘要中文论著摘要第一部分:何学红教授学术思想及运用肾衰方加减治疗慢性肾脏病临床经验总结目的：整理并总结何学红教授临床治疗经验和学术思想。内容：1.何学红教授学术思想主要源自中医“四大经典”、《脾胃论》和《医学衷中参西录》。2.何学红教授认为慢性肾脏病的病因主要为先天不足、饮食不节、劳逸失度、外感六

8、淫和年老体衰等；此外，久病迁延所产生的痰、湿、瘀和毒等病理产物亦是