局部ras对骨髓间充质干细胞心肌缺血保护作用的影响

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1、分类号：R96单位代码：10312密级：学号：20122043博士学位论文题目：局部RAS对骨髓间充质干细胞心肌缺血保护作用的影响研究生：刘超指导教师：李庆平教授学科专业：药理学学院名称：基础医学院完成时间：二一〇五年五月南京医科大学学位论文原创性声巧，独立进行研巧工作本人郑重声明：所呈交的论文是本人在导师的指导下所取得的成果，本论文不包含任何其他。除了文中特别加从标往引用的内容外个人或集体已经发表或撰写的成果作品。对本文的研巧做出重要贡献的个人和集体，均己在文中明确方式标明。本人完全意识到本声明的法律后果由本人承担。作者签名：日期：＞０１玉年心月户日

2、导师签名期：）０年石月作日＾口ｉｊＴ学位论文版权使用授权书＼本学位论文作者完全了解学校有关保留、使用学位论文的规定，同意学校保留并向国家有关部口或机构送交论文的复印件和电子版，允许论文被查阅和借阅。本人授权南京匿科大学可Ｗ将本学位论文的全部或部分内容编入有关数。、据库进行检索，可科采用影印缩印或扫描等复制手段保存和汇编本学位论文’＂■本学位论文属于（请在从下相应方框内打Ｖｏ：。１、保密□，在年解密后适用本授权书２、不保密１１。：年月日作者签名：玉妓日期）。咬＾导师签名日期：年＾月户曰目录英文缩略词表···················

3、·······························································1摘要······························································································3Abstract··························································································6前言································

4、····························································10第一部分血管紧张素II预处理对骨髓间充质干细胞心肌缺血保护作用的影响12引言······················································································12材料与方法·············································································13结果····················

5、··································································23讨论······················································································31第二部分Ace2基因过表达对骨髓间充质干细胞心肌保护作用的影响··········35引言······················································································35材料与

6、方法·············································································37结果······················································································52讨论······················································································65参考文献·····························

7、·························································71文献综述······················································································82博士期间科研成果·········································································110致