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1、抗生素的不良反应（Adversereactionsofantibiotics）Adversereactionsofantibiotics[Abstract]objectivetohelpcliniciansunderstandtheadversedrugreactionsofantibioticsandpromoterationaluseofantibioticsinclinic,soastoensurethesafety,effectivenessandrationalityoftheuseofantibiotics.Methods:reviewofliteratu
2、refromallergicreactionandtoxicity,specificreaction,doubleinfection,drugcombinationcauseoraggravateadversereactionsandotheraspects,summarizestheantibioticadversedrugreactionsandclinicalharm.Resultstheadversereactionsofantibioticscanbepreventedandcontrolled,andtheclinicalmonitoringshouldb
3、epaidattentiontoduringtheprocessoftakingdrugs.Conclusiontheadversedrugreactionsofantibioticsshouldbepaidmoreattentiontobyclinicians.Keywords]antibiotics;adversereactionsAdversedrugreactionsarecommoninclinicalmedication.Itrefersnotonlytothesideeffectsofdrugs,butalsotothetoxicity,specific
4、reactions,allergicreactions,secondaryreactions,etc.[1].Antimicrobialagentsarethemostcommonlyuseddrugsinclinic,includingantibiotics,antifungi,antituberculosisandantibacterialagents.Amongthem,therearethemostvarietiesandquantitiesofantibioticsusedinclinic.Atpresent,therearemorethan100kinds
5、ofantibioticscommonlyusedinclinic.Antibioticshavesavedcountlesslives,buttheirclinicalusehasalsocausedsomeadversereactions[2].Theadverseclinicalconsequencesofantibioticadversedrugreactionsaresevere.Afterafewsecondstoafewhoursorevenalongperiodoftimeafterthedrugwithdrawal,adversereactionsc
6、anoccur.Commonallergicshock,fixeddrugeruption,urticaria,vascularedemaandotherallergicreactions,gastrointestinalreactions,aplasticanemia,etc.,andevencausedeathofpatients(3).Therefore,tostrengthenthesupervisionandrationaluseofantibioticsinthecourseofclinicalmedicationisofgreatsignificance
7、toreducetheincidenceofadversereactions[4].1allergicreactionsAntibioticinducedallergicreactionsaremostcommon[5],mainlyduetopossibleimpuritiesinthedrug,aswellastheeffectsofoxidation,decomposition,polymerization,degradationproductsinvivo,orindividualdifferencesinthepatient.Allergi
